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Biomedical subjects

R Brenot

Publications and source records attributed to R Brenot.

54 records · Page 3Linked to original sources

[Attempt at in vitro decalcification of aortic valves using various types of lasers].

The effects of three types of laser were studied in vitro on calcified aortic valves removed in the course of valve replacement. These were: 1) argon laser; 2) Nd-YAG laser with a long (1 ms) impulse, and 3) Nd-YAG laser with a short (10 ns) impulse. With the first two types of laser, lesions of carbonization and fragments detached from the areas treated were observed. With the 10 ns ND-YAG laser, a mean energy of 100 mj per shot excavated the calcified valves by drilling holes that were 0.5 to 1.5 mm in diameter and had clear-cut non carbonized borders. No residue was found during the procedure: the substance was simply vaporized. The splitting of several calcareous nodules on a valve made it more pliable. If it were possible to transfer this high peak energy onto a flexible optic fibre, the aortic valves could be decalcified by interventional catheterization.

Calcinosis↗

[Coronarography in the study of myxoma. Apropos of a case diagnosed by this technic].

In a 59 years old woman presenting a rudimentary picture of myocardial infarction, ventriculograms confirm a limited necrosis and coronarography shows an abnormal vascular image, evoking an intracardiac tumor, while the arteries are free of atherosclerosis or thrombosis on angiography. Although auscultation and echography are normal, the diagnosis of myxoma will be confirmed by angiocardiography, then by surgery and pathology. The advantage of selective coronary angiography in myxomas is considered with 24 cases from the literature having undergone this examination, including 20 cases, among which ours, which present an aspect of "tumoral vascularisation". The particularities of coronarography (aneurysms, embolic obstruction, origin and aspect of hypervascularisation) are analyzed. This technique appears very useful, not only to detect a complication of the tumor or an associated coronaritis, but also to help in the diagnosis of myxomas in cases where angiocardiography or mostly echocardiography are deficient.

Coronary Angiography↗

[Pseudotumoral mitral endocarditis. Diagnostic and therapeutic problems apropos of a case report with review of the literature].

The authors report an observation of infectious endocarditis of the mitral valve with voluminous pseudo-tumoral growth. The developmental, symptomatic and etiological characteristics of this form of endocarditis were specified through a review of the literature. Echocardiography provides the best means of early detection of these large vegetations but it is not always easy to distinguish them from other left intra-auricular tumors, more especially as several cases of infectious myxoma have been described. Spontaneous development of mitral endocarditis is very harmful, as are infected left intra-auricular tumors, and surgical treatment of these disorders seems essential as soon as the infectious process has been arrested.

Adolescent↗

[Systolic pressure index at the ankle, a "beacon" of long-term monitoring of lower-limb arteriopathy].

Data is provided to demonstrate the reliability of measuring the systolic pressure index (SPI) for surveillance of lower limb arteriopathy (mainly during postoperative follow-up), the aim being to establish a simple, rapid and reliable surveillance test of high decisional value. Reproducibility of SPI values was studied in two series of patients (personal and collective) and on variations of SPI before and after reconstructive arterial surgery, as well as in cases of arterial bypass degradation. The following threshold values, beacon of the surveillance, were retained: --variations of 15% in relation to a reference examination: non-significant, --variations of 20 to 30%: probably significant, --variations of more than 30%: significant. A drop of 30% or more of the SPI in relation to a postoperative reference value during surveillance after reconstructive arterial surgery suggests the need for a follow-up angiography to detect possible lesions that could affect bypass permeability, whatever the patient's symptomatology.

Ankle↗

[Systemic arterial hypertension caused by discharge of catecholamines following ligation of ductus arteriosus].

A case of severe systemic hypertension due to catecholamines discharge after ligation of a large patent ductus arteriosus in an 8 months old child is reported. The blood pressure was corrected by the association of alpha- and betablocker drugs which were withdrawn on the 15th post-operative day without recurrence. Transient increases in blood pressure are quite common after closure of a patent ductus arteriosus with a large shunt. Persistent hypertension greater than 160/110 mmHg is rare. It always regresses but may sometimes cause complications. Hyperactivity of the sympathetic nervous system has already been suggested as a possible cause. Massive discharge of catecholamines and the spectacular effect of the association of alpha- and betablocker therapy, reported here apparently for the first time, provide additional evidence in favour of this hypothesis.

Catecholamines↗

[Early rehabilitation of vascular amputees. Value of the multipurpose prosthesis].

After a recall of surgical indications and of technical points of the lower limbs amputations in arteriosclerosis disease, the authors report their experience of early rehabilitation. They define the aims of the rehabilitation and the means to reach it. Among these, a multipurpose prosthesis made by them, authorized their patients to an early walk training. The results are analysed with 86 patients rehabilitated in 2 years by this method. They have 49 good results/51 with amputation below the knee, 31 good results/35 with femoral amputation. The mean age of the patients is 72.

Amputation, Surgical↗

[Aortic insufficiency associated with ventricular septal defect and a coronary-right ventricle fistula after bacterial endocarditis: surgical correction of 3 lesions].

The authors report a case of Staph-aureus endocarditis on preexisting aortic incompetence. Two complications were observed during the course of the infection: ventricular septal defect, rare but classical, and coronary-right ventricular fistula, a complication not previously described to the best of the author's knowledge. Before the onset of endocarditis a continuous murmur had not been detected clinically or by phonocardiography. This sign appeared while the patient was receiving effective antibiotic therapy. The diagnosis, suggested by the clinical signs in a patient in cardiac failure, was confirmed by catheterisation. This type of complication, already described in peripheral vessels, may be understood when the extent of the lesions at the right coronary cusp, near the septum and right coronary ostium, are appreciated. A good surgical result was obtained due to early operation of the three lesions.

Aortic Valve Insufficiency↗

[What complementary examinations to demand in chronic venous insufficiency?].

The diagnosis of chronic venous insufficiency (CVI) is first of all a clinical diagnosis. Subsequent investigations are useful to elucidate the underlying abnormalities in the venous system and to quantify their severity. Continuous wave doppler ultrasound is the basis test. Duplex scanning is useful for the study of popliteal and tibial veins reflux. The others non invasive techniques aim to investigate patients with severe CVI. But it seems necessary to be very careful with the methodologies used with these tests, and there is a need for a test of the whole calf venous pump function. Venographic studies are performed only if it is necessary to complete the non invasive tests data, before surgical treatment of a postthrombotic syndrome or of congenital deep venous reflux, or when a rare form of CVI is suspected. Venography remains the better test for the study of the anatomy of the venous system, but it is no longer the gold standard for the investigation of CVI.

Chronic Disease↗