Biomedical subjects

R Brookes

Publications and source records attributed to R Brookes.

21 records · Page 2Linked to original sources

PubMed1984

Urinary thiamine excretion after oral physiological doses of the vitamin.

Urinary thiamine excretion has been measured in healthy subjects after oral physiological doses of the vitamin. There was a highly significant correlation between the oral dose and the urinary excretion. However, there was considerable overlap between the baseline values and the urinary excretion following doses up to 1000 micrograms. It is recommended that repeated daily measurements are made to differentiate baseline excretion from that recorded after oral physiological doses. This study may have relevance to the monitoring of dietary fortification programmes with thiamine.

Adult↗

PubMed1967

Dense cultures of Neisseria gonorrhoeae in liquid medium.

Cultivation of Neisseria gonorrhoeae was effected in a conical glass culture vessel surrounded by a constant-temperature water jacket, and with facilities for stirring, aeration, and pH measurement and control. With the use of an aerated peptone-based medium, containing polypropylene glycol to prevent foam build-up, the yields obtained over the pH range from 5.8 to 7.4 were determined. The greatest yield was obtained at pH 6.4 when the dry weight was 1.5 g/liter. At pH 7.2 to 7.6, lysis was extensive.

Complement Fixation Tests↗

PubMed1967

Influence of pH on the growth characteristics of Neisseria gonorrhoeae in continuous culture.

A series of three continuous cultures of Neisseria gonorrhoeae was performed at pH values ranging from 6.4 to 7.2, with an average duration of 3 weeks. The maximal yield obtained was 1.12 mg/ml at a pH of 6.75 and a dilution rate of 0.26 per hr. Some morphological variations were observed at lower dilution rates, but complement-fixation titers remained stable for the duration of the cultures.

Acetates↗