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Biomedical subjects

R Buchwalsky

Publications and source records attributed to R Buchwalsky.

At least 37 records · Page 2Linked to original sources

Improved graft patency with anticoagulant therapy after aortocoronary bypass surgery: a prospective, randomized study.

We conducted a prospective, randomized study to evaluate the influence of oral anticoagulation on graft patency early after aortocoronary bypass surgery. Eighty-nine patients who received 251 distal venous anastomoses were treated with phenoprocoumon, a vitamin K antagonist, starting on the seventh postoperative day; 84 patients with 238 distal venous anastomoses received no anticoagulation. Both groups were comparable with respect to age, exercise hemodynamics, extent of coronary disease and left ventricular dysfunction. In each group, 2.8 distal anastomoses were constructed per patient. Graft patency after surgery was 90.4% in the treatment group and 84.6% in the control group (p less than 0.015). All anastomoses were patent in 81% and 67% of patients, respectively (p less than 0.02). Flow measurements in 279 grafts suggest that grafts with a flow of less than 90 ml/min benefit from oral anticoagulation. No graft with a flow of more than 90 ml/min was occluded.

Adult↗

[Partial atrial standstill with sick-sinus-syndrome accompanying a case of cardiomyopathy (author's transl)].

In a patient with cardiomyopathy of unknown etiology and clinical manifestation of SSS (sick-sinus syndrome) the electro-physiological examination and the registration of pressure curves indicated a mechanical and electrical partial standstill of both atria. Some electro-physiologically interesting phenomena found during the His-catheterization are described.

Cardiac Catheterization↗

[Subclavian steal syndrome: long-term course over 3 years spontaneously and postoperatively (author's transl)].

It was studied development of Subclavian Steal Syndrome in 27 patients postoperatively and spontaneously over a period of 3 years. It was seen a high quote of spontaneous recovery of cerebral symptoms, on the other side there was a lack of complete remissions of cerebral symptoms after vascular operation. Vascular operation is only indicated in syncopal and severe ischemic brachial symptoms.

Diabetes Complications↗

[New experiences in the diagnosis of the sick sinus syndrome (correlation between clinical symptoms, long-therm ecg monitoring, atropine- and exercise testing and sinusnode recovery time) (author's transl)].

The tests recommended for establishing the diagnosis Sick Sinus Syndrome (SSS) were carried out on 36 patients with non-drug-induced Sinusbradycardia (16 symptomatic, 20 asymptomatic) and their resp. diagnostic value was then analysed. Contrary to previous publications, response of heart frequency to exercise testing was normal in all subjects as well as response to intravenous Atropine administration with the exception of 3 cases. A good correlation was found between typical arrhythmias in long-term Ecg monitoring and clinical symptoms. A pathologically prolonged Sinus Node Recovery Time (SNRT) is found in the same number of symptomatic and asymptomatic subjects, frequency-corrected SNRT shows the same results. Shortening of SNRT after Atropine is the more pronounced, the longer SNRT was before Atropine administration. Non-normalization and paradoxical prolongation of SNRT after Atropine have also been observed. In 8 patients stepwise progressive atrial pacing beginning with pacing-frequencies of 70 p.m. was performed before and after Atropine administration. Observation of the effect of Atropine on SNRT may prove to be more important for prognosis and treatment of the SSS than the finding of a prolonged SNRT for establishing the diagnosis. The diagnosis "SSS" should not be based on a pathologically prolonged SNRT alone. Analysis of long-term Ecg monitoring and clinical symptoms should be the main diagnostic tool.

Adult↗

[Clinical course of arteriosclerosis of coronary and lower limb arteries (author's transl)].

The clinical course of arteriosclerosis was evaluated in 9 patients with coronary sclerosis and in 25 with peripheral arterial occlusive disease by means of repeat angiographies following primary angiography after 22.5 and 36.6 months, respectively. During the period of observation arteriosclerosis had progressed in all cases except in two patients with peripheral arterial occlusive disease. Despite intensive therapeutic efforts including control of risk factors, dietary care, guided or unguided exercise and the attempt to change unsatisfactory living conditions, progression of arteriosclerosis could not be interrupted. If treatment delayed progression of arteriosclerosis cannot be decided. All vascular areas were affected indiscriminately by progression and no particular localisation was preferred. Intensive exercise does not seem to delay progression of arteriosclerosis.

Angiography↗