Cervical neurenteric fistula causing recurrent meningitis in Klippel-Feil sequence: case report and literature review.
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Biomedical subjects
Publications and source records attributed to R C Bishop.
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High-dose, intravenous immunoglobulin therapy may be effective in elevating low platelet counts in nonpregnant patients with autoimmune thrombocytopenia purpura (ATP). We used immunoglobulin successfully on two pregnant women with ATP who had been refractory to high-dose corticosteroid therapy. The 5-day infusions were started at 12 and 29 weeks' gestation, and the subsequent uncomplicated vaginal deliveries occurred after the shortest reported interval (8 days) and longest (28 weeks) following a single immunoglobulin infusion. A splenectomy was avoided, and no adverse maternal or neonatal effects were apparent.
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Response patterns and the limits of loudness judgement accuracy were explored in a clinical presentation of the alternate binaural loudness balance (ABLB) procedure, and compared across the two methodological alternatives of using the better or poorer ear as reference ear. It was found: 1) that in the range of judgement uncertainty, responses were strongly influenced by stimulus presentation order; 2) that the magnitude of the range of uncertainty was similar across both methodologies. A suggested clinical procedure which controls for these effects is presented as an Appendix.
Although iron in minute amounts is necessary for the metabolism of most cells, it produces damage if present in excess. Clinical tools for the evaluation of iron stores include serum iron concentration, transferrin saturation, deferoxamine test, Prussian blue stains of liver and marrow, and serum ferritin concentration. Serum ferritin concentration is an excellent screening test for iron deficiency or excessive iron stores. If excessive iron stores is diagnosed, the iron should be removed with phlebotomies or chelation therapy.
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