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Biomedical subjects

R C Cook

Publications and source records attributed to R C Cook.

At least 37 records · Page 2Linked to original sources
PubMed1980

Cardiac toxicity of perchloroethylene (a dry cleaning agent).

Perchloroethylene analysis was performed on plasma of a 24-year-old white man who presented with a history of premature ventricular beats, dizziness, and headaches. There was no clinical, electrocardiographic, radiologic, or echocardiographic evidence of heart disease. The occurrence of premature ventricular beats and the patient's symptoms were more pronounced when the plasma level of perchloroethylene was high (3.8 ppm). Removal of exposure to perchloroethylene relieved the patient's symptoms and the premature beats completely disappeared.

Adult↗
PubMed1978

Short- and long-term effects of para-chloroamphetamine on ingestive behavior.

Para-chloroamphetamine (PCA) produces short-term decreases in eating and drinking. PCA also chronically decreases brain serotonin concentration following a single peripheral injection. The present investigation assessed short- and long-term effects of PCA on ingestive behavior and body weight in greater detail. Following an adaptation period, PCA, 0.0, 1.0, 2.0, 5.0 and 10.0 mg/kg, were administered IP, to free feeding rats. A decrease in food and water consumption was observed during the 0--24 hr postinjection period. During the 24--48 hr period, water consumption was significantly increased compared to baseline. Food intakes during this same period returned to baseline levels. No long-term effects on ingestive behavior or body weight were seen during the following 30 days.

Amphetamines↗
PubMed1978

Tracheal compression as a cause of respiratory symptoms after repair of oesophageal atresia.

A case of tracheal compression in an infant after repair of a tracheo-oesophageal fistula and oesophageal atresia is reported. Tracheopexy completely relieved the symptoms of apnoeic attacks, cyanosis, and convulsions. We suggest that tracheal compression in infants and children with repaired oesophgeal atresia can not only cause life-threatening attacks but also be responsible for recurrent chest infections. All infants and children with signs and symptoms of tracheal compression as shown by the presence of a barking type of cough, recurrent chest infections, or persistent mild respiratory symptoms should be referred for thorough investigation of the tracheobronchial tree.

Endoscopy↗
PubMed1977

Microbiological investigation of meat wholesale premises and beef carcases in Johannesburg.

Microbiological surveillance by swabbing meat wholesaler premises revealed ineffective cleaning and build-up of bacteria. Proper cleaning, sanitation and handling resulted in a vast improvement during 1975-77. Beef samples from the neck of carcases in the wholesale trade were investigated by microbiological methods. Excessive total bacterial counts were obtained from numerous carcases. Most carcases carried coliform organisms. Roughly 90% of carcases were contaminated with E. coli I; counts exceeded 10(3)/g in 18% of carcases tested. Twenty serotypes of Salmonella were identified. Salmonella contamination decreased from nearly 5% in 1975 to less than 0,5% in 1977, and S. aureus contamination from 52% to 36% during the same period. Approximately 30% of carcases revealed contamination with unidentified clostridial species. The results indicate the need for stricter control over the production and slaughter of animals and over the handling of carcases in the wholesale trade.

Animals↗
PubMed1976

Experiences in the diagnosis of brucellosis in dairy cows.

The Milk Ring, Serum Agglutination, Biological, Mercaptoethanol and Rose Bengal Plate Tests were used in combination to diagnose brucellosis in cows in some herds supplying milk to Johannesburg. The work was done in conjunction with routine testing of bulk milk supplies for public health control. 4 769 cows in more than 76 herds were involved in the tests. Results confirm that no single test can demonstrate all infected cows in a herd and that repeated testing is necessary. In an infected herd in which Strain 19 adult vaccination has been used some negative and suspicious cows will have to be sacrificed in eradicating the disease.

Agglutination Tests↗
PubMed1976

The incidence and sources of penicillin in milk supplied to the city of Johannesburg.

The incidence of penicillin in bulk milk supplies to the city has varied from 1,2% to 2,6% over the past five years, and 3,2% of 366 pasteurised milk samples examined in 1975 were found to contain penicillin. Investigation of the sources revealed numerous instances of producers, milkers and veterinarians who had not acted responsibly in regard to the marketing of milk from treated cows. Details are provided. The legal and professional obligations of the veterinarian are emphasized. Reference is made to the dye marking registered intramammary formulations for farmer treatment of mastitis.

Animals↗
PubMed1970

Appeal to doctors.

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Ethics, Medical↗