Plasma deoxyribonucleic acid concentrations of women in labor and umbilical cords.
The concentration of deoxyribonucleic acid (DNA) in plasma from 30 women in labor and plasma from the umbilical cords was determined with a rapid, inexpensive, and simple fluorometric method. These concentrations of DNA were compared to the plasma DNA concentrations of nonpregnant women. The mean plasma DNA concentration of women in labor was significantly lower than the mean plasma DNA concentration of nonpregnant women in the use of 99 per cent confidence limits. The mean plasma DNA concentration of umbilical cords during the third stage of labor was significantly lower than the mean plasma DNA concentrations of women in labor with the use of 99 per cent confidence limits and of nonpregnant women using 99.9 per cent confidence limits.