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Biomedical subjects

R C Meyer

Publications and source records attributed to R C Meyer.

At least 55 records · Page 3Linked to original sources
PubMed1971

Polyserositis Induced by Escherichia coli in Gnotobiotic Swine.

The oral administration of an 18-hr broth culture of Escherichia coli 06: isolated from a cat to 3-day-old gnotobiotic (germ-free) piglets resulted in bacteremia and polyserositis. Sixteen pigs, selected from four litters, were used in the study. E. coli of the same serotype employed was the only bacterial agent demonstrable and recovered from moribund and dead piglets. Attempts to recover virus or PPLO (mycoplasma) from these animals were unsuccessful. A polyserositis syndrome was not encountered among neonatal pigs in experiments with 14 other serotypes of E. coli; hence it was considered to be a syndrome closely associated with the infection caused by this particular strain of E. coli.

Journal Article↗
PubMed1971

Escherichia coli Isolated from Domestic Animals Pathogenic for Gnotobiotic Piglets.

Three strains of Escherichia coli isolated from infectious processes in a calf, a dog, and a cat were examined for their capacity to produce disease or death, or both, in newborn gnotobiotic piglets. The O groups represented by these particular strains of E. coli were O4: (canine origin), O6: (feline origin), and O39: (bovine origin). All three isolates upon oral administration proved to be pathogenic. Infection with the E. coli O4: (canine) or O39: (bovine) consistently produced signs of enteric coli-bacillosis and death in all 1- and 3-day-old piglets within 24 to 48 hr. The O6: (feline) isolate, on the other hand, produced a marked polyserositis and generally required 6 to 7 days to kill a piglet. Only the respective type of E. coli used in the particular trial was recovered from the diseased piglets. These findings suggest the possible role of domestic animals and household pets in the spread of potentially pathogenic E. coli to other species.

Journal Article↗
PubMed1971

Serological identification of Escherichia coli isolated from cats and dogs.

In a group of 112 cats, examined during an outbreak of diarrhea, 104 (92.8%) yielded Escherichia coli with identifiable O groups as compared to 12 (21.8%) of 55 control cats apparently free of intestinal ailments. E. coli group O6 occurred in 49.1% of the cats with diarrhea, and persisted in this group of cats at about the same rate when examined for a period of ten months. E. coli group O6 was not isolated from the control group. Specimens were also collected from dogs with various clinical signs. E. coli O4 and O6 strains appear to be important potential pathogens for canine species and were found to spread from one dog to another when in close contact. E. coli group O4 was identified in ten and O6 in three of 14 dogs examined. All isolates in which the O group could be identified were hemolytic.

Agglutination Tests↗
PubMed1968

Experimental exposure of pigs to infectious bovine rhinotracheitis (IBR) virus.

Thirteen specific-pathogen-free pigs were used in an experiment to determine the pathogenicity of IBR virus for pigs. Three pigs were used as controls, eight were exposed to IBR virus by either the intravenous, subcutaneous, intratracheal, or intranasal route, and two pigs served as contact controls. The clinical response consisted of a temperature rise, depression and variable lymphocytosis. The major tissue alterations were interstitial pneumonitis, and peribronchiolitis with round cell aggregates and giant cell formation. IBR virus was not recovered from any of the pigs. A serologic response was detected in only the pig injected intravenously.

Animals↗
PubMed1966

An experimental viral pneumonia in swine.

Pneumonia resulted when a porcine entero-virus, ECPO-6, was inoculated intranasally into four and six week old, colostrum deprived, specific pathogen free piglets. Clinical signs consisted of mild depression, rapid breathing with rectal temperatures reaching 104-105 F five to six days after infection. Pneumonic lesions, both gross and microscopic were present 21 days post infection. Although the virus was readily isolated from the cecal contents of infected pigs three weeks after infection the virus was not recovered from infected lungs after the first 7-10 days.

Animals↗