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Biomedical subjects

R C Nealeigh

Publications and source records attributed to R C Nealeigh.

7 recordsLinked to original sources
PubMed1978

Echocardiographic assessment of normal and abnormal valvular function in Beagle dogs.

Echocardiograms were obtained from 5 young Beagles (4 to 5 years of age) and from 4 old Beagles (12 to 14 years of age). Ultrasound surface transducers and esophageal transducers were used on all animals during anesthesia. Triplicate studies were performed on the 5 young Beagles over a 2-week period. The left atrioventricular valve and aortic root were identified by both procedures, whereas the right atrioventricular valve dynamics could be viewed with difficulty by the transcutaneous approach. Suitable recordings of the pulmonary valve were not obtainable with either technique. Abnormal left atrioventricular valve dynamics, characterized by a decreased closing velocity of the left atrioventricular septal cusp and increased valve thickness, were observed in 2 of the 4 aged dogs, using echocardiography. Excellent correlation between the 2 methods was evident, and minimal variation in results from one recording session to another occurred.

Animals↗
PubMed1976

Venous ultrasound catheter-tip technique for evaluation of arterial hemodynamics.

A variety of devices has been used for measuring flow properties of deep-lying arteries, but many have limitations. This paper describes a relatively nontraumatic intravenous approach which uses a catheter in connection with a pulsed ultrasonic Doppler velocity meter (PUDVM) and an ultrasound echo track. The venous ultrasound catheter (VUC) has permitted measurements of local instantaneols blood velocity, flow, and wall motion in the abdominal aorta and iliac arteries of beagle dogs; evaluation studies have been conducted to compare the VUC recordings with an independent method for measuring blood flow and wall motion. Coupling of this catheter-tip device with the PUDVM and echo track provides chronic measurements of hemodynamic parameters in these deep vessels which were virtually impossible to obtain previously. This technique may prove useful in monitoring vessel pathology longitudinally as well as in basic experimental situations requiring flow and arterial wall mechanical properties.

Animals↗
PubMed1976

A venous pulse Doppler catheter-tip flowmeter for measuring arterial blood velocity, flow, and diameter in deep arteries.

Numerous schemes have been used for measuring hemodynamic properties of deeply lying arteries; however, all have their limitations. This paper describes a new relatively nontraumatic intravenous approach that uses a catheter in connection with a pulsed ultrasonic Doppler velocity meter (PUDVM) and an echo track. The catheter was initially tested in a hydraulic model system for calibration of velocity and flow parameters. Lately, the catheter has permittted measurements of local instantaneous blood velocity, flow, and wall motion characteristics in adult Beagle dogs in the abdominal aorta and iliac artery. Evaluation studies have been conducted to compare the catheter-tip recordings with an independent method for measuring blood flow and wall motion. Coupling of this catheter-tip device with the PUDVM and echo track provides chronic measurements of hemodynamic parameters in these deep vessels which were virtually impossible to obtain previously. This technique may prove useful in monitoring vessel pathology longitudinally as well as in basic experimental situations requiring flow and arterial wall mechanical properties.

Animals↗