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Biomedical subjects

R C Reba

Publications and source records attributed to R C Reba.

At least 145 records · Page 8Linked to original sources
PubMed1975

Patterns of excretion of radioactive chelates in obstructive uropathy.

Radioactive chelates such as 99mTc-DTPA are advantageous in ranal imaging, particularly in defining functional and morphological abnormalities of the excretory tract. In a review of more than 200 studies, 19 cases of lower-tract disease were diagnosed by the gamma camera image alone. In 16 of them, the diagnosis was confirmed by excretory urography. Normal radionuclide patterns are described and compared with the characteristic findings in caliectasis, hydronephrosis, and hydroureter. By facilitating evaluation of renal perfusion, renal glomerular function, and gross renal structure as well as good difinition of excretory function, radioactive chelate imaging is ideally suited for use as general screening test.

Adult↗
PubMed1975

Extra-osseous localization of 99Tcm-Sn pyrophosphate.

99Tcm-Sn pyrophosphate bone scans of 250 patients referred for skeletal metastatic survey were analysed to determine the frequency of abnormal extra-osseous localization and the various pathological causes. Twenty-six patients demonstrated abnormal extra-osseous concentration. There were three false positives. Sixty-five per cent of the extra-osseous lesions concentrating pyrophosphate were malignant (carcinoma of lung and breast, metastatic hepatic carcinoma, chondrosarcoma) and the remainder were benign lesions, e.g. sarcoidosis, soft-tissue calcification, post-surgical and irradiation sites. An incidental finding was the unusual frequency of accumulation of pyrophosphate in various joints, especially the knees and shoulders in asymptomatic patients above 70 years of age.

Age Factors↗
PubMed1975

Cobalt-labeled bleomycin--a new radiopharmaceutical for tumor localization. A comparative clinical evaluation with gallium citrate.

The efficacy of 57Co-labeled bleomycin as a tumor-scanning agent was evaluated in 50 patients with malignant tumor. In terms of sensitivity, labeled bleomycin was found to be a superior agent for malignant tumor detection when compared with 67Ga-citrate (p less than or equal to 0.005). Maximum sensitivity (96%) was found in epidermoid carcinomas. Because of rapid blood clearance and rapid excretion by the kidneys, interpretation of 57Co-bleomycin scans is facilitated.

Adenocarcinoma↗