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Biomedical subjects

R C Russo

Publications and source records attributed to R C Russo.

11 recordsLinked to original sources
PubMed2002

Development of marine water quality criteria for the USA.

The US Environmental Protection Agency has developed guidelines for deriving numerical national water quality criteria for the protection of aquatic organisms and their uses. These guidelines provide the method for deriving water quality criteria, including minimum data base requirements, data evaluation procedures, and calculations. The guidelines have been in place for a long time, and states have used them to derive water quality standards for their water bodies. More recent efforts have been directed towards the development of technical guidance based on the concept that bioassessment and biocriteria programs for estuaries and near coastal waters are interrelated and are critical components of comprehensive water resource protection and management. This is a holistic approach to protection and management, integrating biological assessments into traditional chemical and physical evaluations and augmenting the established water quality criteria. The method for deriving water quality criteria and the approach for biocriteria development for marine systems are described.

Animals↗
PubMed1993

Treatment of nasal surgery complications.

There are numerous articles on how to prevent and manage the untoward aesthetic and functional results of nasal surgery. However, little has been written on the disabling or life-threatening complications of nasal surgery. Recent series have reported the incidence of these complications to be between 5% and 18%. Severe complications from nasal surgery can be divided into the following four categories: hemorrhagic, infectious, traumatic, and miscellaneous. Postoperative hemorrhage is the most commonly seen problem. However, there are numerous case reports of toxic shock syndrome associated with nasal surgery and even of intracranial complications. In this article, we provide an overview of these complications and their treatment.

Anesthesia↗
PubMed1993

The management of septal perforations.

Twenty-five patients with septal perforations were seen between July 1, 1983, and June 30, 1989. There were 16 males and 9 females, who ranged in age from 21 to 72 years, with the median age of 41.7 years. The majority of the perforations were traumatic in origin, with 19 cases seen following septal surgery, and were between 1.5 and 2.5 cm (20), with a range of 0.5 to 4 cm. All were located at the posterior border of the quadrilateral cartilage at the vomer-ethmoid junction. All but 3 patients underwent surgical repair, and successful closure was achieved in all but 3. However, only 1 patient remained symptomatic after surgery. The surgical technique employed includes an external rhinoplasty approach, septal and intranasal mucosal flaps, and an autograft of mastoid periosteum or temporalis fascia.

Adult↗
PubMed1992

External rhinoplasties: indications for use.

The technique, indications and role of external rhinoplasty in nasal surgery are presented. The technique has been utilised in 563 patients with a minimum follow-up of 18 months. The external approach has been especially helpful in the severely twisted nose, secondary rhinoplasty, augmentation rhinoplasty, congenital deformities of the nose, closure of septal perforations and in the teaching and learning of rhinoplasty. In this series there were no reported complications attributable to the external approach.

Adolescent↗
PubMed1991

Vascular smooth muscle cell proliferation and its therapeutic modulation in hypertension.

The increased growth potential of vascular smooth muscle cells (VSMCs) represents one of the crucial anomalies responsible for the development of essential hypertension, diabetic macroangiopathy, and atherosclerosis. The exaggerated response to growth factors of VSMC from spontaneously hypertensive rats (SHRs) persists in culture when compared with normotensive Wistar-Kyoto control rats, indicating an intrinsic defect in the hypertension-producing mechanism. This greater proliferation is characterized by two intermediate phenotypes: (1) accelerated entry into the S phase of the cell cycle, which results from hyperresponsiveness to epidermal growth factor and platelet-derived growth factor, and (2) abnormal contact inhibition. The enhanced expression of transforming growth factor beta 1 (TGF-beta 1) messenger ribonucleic acid in SHRs precedes this altered contact inhibition, and only VSMCs from SHRs respond to exogenously added TGF-beta 1 at a high cell density, which suggests that abnormal TGF-beta 1 autoregulation may be implicated in the second phenotype. Platelets contain major growth factors for VSMC. Platelet extracts from hypertensive and diabetic patients present augmented growth-promoting activity on VSMCs, which is most evident when both diseases occur simultaneously. Growth-promoting activity may be further influenced by antihypertensive therapy. This growth-promoting activity is increased by hydrochlorothiazide but not by indapamide, atenolol, or captopril in diabetic hypertensive and nondiabetic hypertensive patients. In conclusion, VSMCs in hypertension manifest an intrinsic growth defect that is modulated by extrinsic platelet growth factors and antihypertensive drugs.

Animals↗
PubMed1990

External rhinoplasty technique.

External rhinoplasty is a valuable tool in the surgical armamentarium of all nasal surgeons. It does not change the dynamics of the operation but offers a new method of exposure. The purpose of this paper is to present our experience with the external rhinoplasty technique in 601 patients, and review the results and complications of this approach to nasal surgery. Two patient reports are presented to demonstrate use of the technique in nasal surgery.

Adolescent↗