Biomedical subjects

R Calay

Publications and source records attributed to R Calay.

11 recordsLinked to original sources

PubMed1992

Emission tomography for assessment of diffuse alcoholic liver disease.

A method of quantitative liver tomoscintigraphy (SPECT) was compared for accuracy with planar scintigraphy (PS) in a group of patients with diffuse alcoholic liver disease. SPECT sensitivity was also compared with that of transmission computed tomography (CT), US, aminopyrine breath test (ABT) and liver chemistries (LC). One hundred and fourteen alcoholic patients with proven liver disease and 17 patients free of liver disease were included. Seven quantitative scintigraphic features and a score, including all criteria were considered. With a specificity of 95%, the sensitivity was 79% in steatosis and 97% in cirrhosis. SPECT showed a better sensitivity than PS (SPECT 89%, PS 66%), especially in patients with steatosis. In the same subsets of patients, SPECT sensitivity also compared favorably with that of transmission CT (SPECT 92%, CT 65%), ultrasonography (SPECT 88%, US 53%) and ABT (SPECT 90%, ABT 63%).

Alanine Transaminase↗

PubMed1987

Thyroid, lipid and other biological variables in elderly patients with asymptomatic autoimmune thyroiditis: a statistical analysis.

Asymptomatic autoimmune thyroiditis (AAT), especially prevalent in elderly women and associated with the presence of thyroid antibodies (HT), is recognized as a precursor of hypothyroidism and is an intermediate between euthyroidism and hypothyroidism. This paper is concerned with the possible modifications of biochemical variables - some of which are not directly related to the thyroid - in patients with AAT. Thirty-seven serum factors were investigated in euthyroid, AAT, and HT subjects over 69 years of age. They were thyroglobulin; microsomal, gastric and adrenal antibodies; LE cells, and thyroid, lipid and immunological variables linked to the inflammatory process. In women the only variable, other than those related to the thyroid, which showed any modification in the AAT state was the cholesterol level. Wholly different observations were made in men, stressing the necessity of separate analysis of male and female data: the thyroid-related variables which were modified in the AAT state are not the same as in women, the cholesterol is not increased but triglycerides, HDL, albumin and inflammatory variables are modified. Furthermore, the lipid variables showed an unexpected age dependency in AAT, but not in euthyroid women (between 69-90 years of age).

Aged↗

PubMed1977