[Congenital "cardio-esophageal" syndromes].
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Biomedical subjects
Publications and source records attributed to R Caldera.
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74 low birthweight infants haematologic findings were studied during the first 24 hours and at the 8th day of life. By statistical methods derived from the multivariate analysis: stepwise multiple regression analysis and factor analysis, correlations were investigated between haemogram data (red cells count, haemoglobin and haematocrit levels and 18 others parameters. Most of the infants with polycythemia have toxaemic mothers and were born after a long gestation: they are affected by intra-uterine growth retardation, have a low glycaemia level but a normal calcaemia level, a large skull perimeter and a small thymus volume. But no correlation was observed between polycythemia and the following data: heart volume, neonatal icterus intensity, reticulocytes and erythroblasts counts.
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alpha-tocopherol and placebo were compared by a double-blind trial to study their preventive effect on secondary anemia in a sample of low birth weight (less than or equal 2,500 g) infants. In the 7th week of life, hematological data from each of the two groups of infants (receiving vitamin E or placebo) were compared either by covariance analysis or by the t test of comparison of means. The infants who were given vitamin E have a higher serum level of vitamin E, a lower hemolysis, a higher erythrocyte count and a higher hemoglobin level than infants given the placebo. No significant difference was observed with respect to hematocrit or reticulocyte count. Thus, it appears that vitamin E has an effect on some of the factors in the anemia of infants of low birth weight.
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