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Biomedical subjects

R Cartsburg

Publications and source records attributed to R Cartsburg.

7 recordsLinked to original sources
PubMed1980

[Treatment of upper-abdominal pain in chronic gastritis. Results of therapy with the motility regulating drug Bromopride].

After discussing the aetiological role of the reflux from the duodenum in causing and maintenance of chronic gastritis, the author studied the effect of bromopride, a drug regulating gastrointestinal motility, on the subjective complaints of individuals suffering from the disease. In a randomized double-blind trial, 31 subjects with upper abdominal complaints, histologically established antrum gastritis and endoscopic signs for disorders of pyloric function were treated with one capsule three times daily of bromopride or a placebo, over a period of three weeks. The positive therapeutic results in 12 of 13 patients on bromopride provide support for the clinical use of a drug regulating gastrointestinal motility in the treatment of duodeno-gastric reflux causing the discomfort of individuals with chronic gastritis. Subjects exhibiting a sensation of fullness and pressure, flatulence, pain in the epigastrium and eructations, were found to be most responsive to bromopride. No relationship between side-effects and drug treatment was observed.

Abdomen↗
PubMed1978

[Acute pancreatitis following gastric secretion analysis by pentagastrin stimulation (author's transl)].

A picture of acute abdomen developed in a 25-year-old patient with recurrent duodenal ulcers after subcutaneous injection of pentagastrin for a gastric secretion test. Laparotomy undertaken for suspected perforated ulcer revealed an acute hemorrhagic pancreatitis. Healing and freedom from complaint occurred rapidly with drug therapy. The following are to be considered as possible causes for pancreatitis after subcutaneous application of pentagastrin: exacerbation of the ulcer, an acute exacerbation of chronic pancreatitis, a direct effect of pentagastrin on the pancreas, increased pancreatic secretion due to the stimulation of gastric acid, reflux of duodenal contents or bile, arterial hypotension with local acidosis in the pancreas. Attention must always be paid to contra-indications of gastric juice analysis.

Acute Disease↗