OBRA '90 and your pharmacy computer system.
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Biomedical subjects
Publications and source records attributed to R Cataldo.
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The antihypertensive efficacy of combination therapy with N-E-A was evaluated during 6 months in 15 patients with hypertension associated with mild to moderate kidney failure. After 6 months a significant reduction of SBP and DBP (p < 0.001), with improvement of creatinine clearance and with no adverse effects on ECG, heart rate and routine laboratory tests test, was observed in 3 patients treated with N 20 mg x 2/d + E 10 mg/d + A 50 mg/d and in 8 patients treated with N 20 mg x 3 + E 10 mg x 2, + A 50 mg x 2. Four patients did not respond to this therapy.
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In the present study, the side effects of d-Penicillamine therapy in 54 patients with rheumatoid arthritis are analyzed. The therapeutic efficacy of the drug is emphasized; but in the meantime, the necessity is also stressed that the choice of this antirheumatic agent must imply the knowledge of the possible complications caused by its use and of the clinical features and laboratory data which would be useful for their early detection.
We present a case of multiple myeloma in which pulmonary calcification was clinically shown by bone scintigraphy and subsequently confirmed at autopsy. It is suggested that, in patients with myeloma, radionuclide bone scanning may be of value for differentiating deposits in the lung due to calcification from those due to other types of pulmonary infiltration revealed by chest X-rays. A thorough review of the relevant literature is presented.