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Biomedical subjects

R Cavallina

Publications and source records attributed to R Cavallina.

6 recordsLinked to original sources
PubMed1984

Morphofunctional findings in adenocarcinoma of endometrium.

Ten cases of adenocarcinoma of the endometrium were studied using histochemical methods for mucopolysaccharides and immunocytochemical methods for the localization of various markers, such as EMA (epithelial membrane antigen), GCDFP-15 (gross cystic disease fluid protein) and CEA. Four cases appeared to contain High Iron Diamine-positive substance and 6 cases were positive using an immunocytochemical method with a polyclonal anti-CEA antiserum. In contrast, no cases stained when a monoclonal anti-CEA antiserum was employed. This suggested that HID- positive material could be a sign of differentiation towards cells with a secretory function.

Adenocarcinoma↗
PubMed1984

Morpho-functional changes in normal cyclic endometrium.

Eight cases of normal endometrium in the early proliferative phase and an equal number of cases in the late secretive phase were stained histochemically for acidic mucosubstances and immunocytochemically for epithelial membrane antigen (EMA), carcinoembryogenetic antigen (CEA) and Gross Cyst Disease Fluid Protein -15 (GCDFP-15) production. Alcian blue positive material was observed in both phases of the cycle, although the distribution was different. Sulphated mucosubstances were only present in the secretive phase. No CEA nor GCDFP-15 immunoreactive material was detected. EMA positive staining was observed in all cases, but the distribution varied according to the two different phases of the cycle.

Adult↗
PubMed1983

Behavior of some steroids in endometrial adenomatous and atypical hyperplasia.

Endometrial adenomatous and atypical hyperplasia are the histopathological pictures that more frequently may develop into an adenocarcinoma. It is believed that a hormonal action may favour the genesis of endometrial cancer. We studied the plasmatic levels of some steroids, considered to be responsible for neoplastic changes, in patients with adenomatous and atypical hyperplasia. With this object we measured plasmatic levels of estrone, estradiol, androstenedione, DHEA-S and testosterone in postmenopausal patients with adenomatous and atypical hyperplasia and in fertile women, both in proliferative and secretory phases. We didn't find any difference in the steroid pattern in the two groups.

Adult↗
PubMed1983

Behaviour of some steroids in postmenopausal women with coelomic ovarian tumors.

In order to study the hormonal pattern in ten postmenopausal women with coelomic ovarian tumors we measured Estrone, Androstenedione, DHEA-S and Testosterone plasmatic levels before and after surgery. Estrone and Androstenedione plasmatic levels were significantly higher in patients with coelomic ovarian tumors than in the control group and they showed a rapid and constant decrease after surgery. Nevertheless we didn't find any ovarian histological picture to explain the hormonal increase.

Adenocarcinoma, Mucinous↗
PubMedDate not supplied

An enzyme-linked immuno sorbent assay for salivary estriol during normal pregnancy.

It has been recently demonstrated that the concentration of Estriol in saliva increases in the course of pregnancy, similarly to the plasmatic concentration of unconjugated and total Estriol. As an alternative to RIA, which is an expensive method and requires a highly specialized laboratory, there is now available a competitive, sensitive and rapid enzyme-linked immuno sorbent assay (ELISA) for Estriol in saliva and plasma. Aim of this study is to compare the levels of Estriol concentration, measured by RIA and by ELISA in saliva and plasma in seven women tested every week from the 30th week to the term of pregnancy.

Adult↗