PubMed Health⌕ Search

Biomedical subjects

R Cella

Publications and source records attributed to R Cella.

35 records · Page 2Linked to original sources
PubMed1983

Cadmium distribution within corn plants as a function of cadmium loading of the soil.

Corn is a widespread crop in some industrialized areas of Northern Italy and Europe where it serves for both animal and human nutrition. In the present paper we examined the distribution of Cd within corn plants grown under both hydroponic and field conditions. The results obtained show that Cd accumulation by different plant tissues may reach saturation without signs of phytotoxicity. Thus cadmium pollution can go undetected even when corn plants are grown in the presence of a consistent amount of Cd. Its accumulation within plant tissues is responsible for the entry of the metal into the food chain. Implications for human and animal nutrition are discussed.

Cadmium↗
PubMed1982

[Hypopotassemia during delirium tremens. Pathogenesis and clinical significance].

The authors have investigated the changes of kalemia and kaluria levels in 40 patients suffering from delirium tremens, and have observed during the acute stage of the illness, a swift fall of kalemia level without an increase of the kaluric excretion. The kalemic values quickly rise up again at the end of the delirium.. The authors think that an adrenergic mechanism is responsible for this quick and transient hypokalemia. The significance of this adrenergic mechanism in the alcohol withdrawal syndrome is at present widely proved.

Alcohol Withdrawal Delirium↗
PubMed1982

[Dupuytren's disease in clinical practice].

The Authors have investigated the incidence of Dupuytren's disease in the field of internal medicine, they have observed a rather high rate in the old people, especially between 60 and 80 years, and point out the significance of metabolic and genetic factors in the pathogenesis and the development of the disease.

Age Factors↗
PubMed1982

[The thyroid hormones in alcoholic liver cirrhosis. Clinical and prognostic aspects].

The Authors confirm the clinical and prognostic importance of the measurement of circulating thyroid hormones - especially of Triiodothyronine (T3) - in evaluating the decompensated phases of alcoholic liver cirrhosis. The assay was performed in 90 patients affected by liver cirrhosis and was compared with the clinical manifestations and other laboratory test: only prothrombin time was showed to be as useful as T3 concentration in following the clinical course of cirrhosis. Low levels of tetraiodothyronine (T4) - if one can rule out the presence of hypothyroidism - are evidence for a bad impending prognosis.

Adult↗
PubMed1981

[Dupuytren's disease. Current etiopathogenetic perspectives].

The Authors after discussing some of the aetiopathogenetic factors of Dupuytren's disease, have studied the behavior of sera glycemic shape after oral load in 368 patients with Dupuytren's disease, finding a impairment tollerance of glucose in the 93.20% of these patients. This suggest that the impairment of the glycemic metabolism still outside of alcoholic pathology is one important factor in the Dupuytren's disease and perhaps in the development of cirrhosis and hepatica fibrosis.

Arteriosclerosis↗
PubMed1981

Increased prolactin reserve in alcoholics.

The prolactin response to oral metoclopramide (10 mg) was investigated in 53 chronic alcoholics (26 with alcoholic cirrhosis and 27 without evidence of liver disease) from two to seven days after alcohol suspension. The response appeared significantly higher in patients than in healthy controls and was not related to the presence of liver disease. This finding may depend on the deactivation of the dopaminergic activities secondary to alcohol suspension; alternatively, ethanol could have a direct action on prolactin secretion.

Adult↗
PubMed1975

Rsistance to streptomycin in a producing strain of Streptomyces griseus.

Streptomyces griseus S 104 was sensitive to streptomycin during exponential growth in a medium which, in the subsequent stationary phase, supported production of the antibiotic in yields above 200 mug/ml. When antibiotic production began cultures developed a tolerance toward their lethal metabolite. This was not due to an increase in pH associated with antibiotic production, since pH effects on streptomycin sensitivity in S. griseus were in the reverse direction. However, the degree of tolerance was directly related to the amount of cell material present. Streptomycin production caused no change in the proportion of resistant variants in the population, nor did it cause the severe inhibition of protein synthesis observed in non-producing cultures exposed to the antibiotic. The lack of an effect on protein synthesis is attributed to the absence of streptomycin with in the cytoplasm since soluble extracts from mycelium harvested in the production phase were inactive when bioassayed immediately after cell disruption. However, they developed antibacterial activity rapidly when heated, and more slowly when incubated at 25 degrees C. The addition of phosphatase inhibitors during incubation prevented the appearance of antibiotic activity, and it was concluded that a small amount of streptomycin phosphate is present in the mycelium during antibiotic production. Differences in (14C) streptomycin uptake suggested that the mycelium was appreciably less permeable to the antibiotic in the production phase than during exponential growth. However, a small amount was taken up and much of it was in the soluble fraction of disrupted cells. Bioassays showed that this 14C-labeled antibiotic within the cells had been partially inactivated, suggesting that conversion of streptomycin to an inactive derivative is involved in the mechanism which protects the organism from its metabolite.

Alkaline Phosphatase↗
PubMed1975

Streptomycin resistance in chloramphenicol-producing strains of Streptomyces species 3022a.

Resistance to low (5 mug/ml) concentrations of streptomycin in agar media was not inherited by all of the surviving population. Outgrowth of cultures in liquid media supplemented with the antibiotic depended upon inoculum size. Antibiotic titers in the supplemented cultures decreased during incubation, and an inactive radioactive product was detected when [14C] streptomycin was used. This low-level resistance is, therefore, attributed to enzymic inactivation of the antibiotic. Growth 10 mug/ml or higher concentrations of streptomycin on agar media was due to selection of resistant variants present in the parent strain. A range of such variants existed, decreasing in frequency as their degree of resistance increased. Examination of one that was resistant to moderate concentrations of streptomycin, (25 mug/ml) and a second that was resistant to high (100 mug/ml) concentrations of streptomycin suggested that both possed ribosomes which had lower affinity for the antibiotic than those of the parent strain, and that tolerance to high levels of streptomycin was due to a resistant ribosomal system for protein biosynthesis.

Acriflavine↗
PubMedDate not supplied

Proliferation-dependent pattern of expression of a dihydrofolate reductase-thymidylate synthase gene from Daucus carota.

The pattern of expression of a carrot dhfr-ts gene was evaluated in different plant organs, in somatic embryos, and in hypocotyl explants induced to dedifferentiate in vitro by the addition of the synthetic auxin 2,4 dichorophenoxyacetic acid. The promoter of this gene was also placed upstream of a uidA (GUS) reporter gene and, using biolistic and protoplasts transient expression assays, was shown to drive a particularly high level of expression in actively growing suspension cells. The results from these expression analyses combined with the presence of putative cell cycle-related cis-acting elements in the dhfr-ts promoter, strongly point to a cell division-dependent expression of this gene.

Cell Line↗