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Biomedical subjects

R Chiari

Publications and source records attributed to R Chiari.

12 recordsLinked to original sources
PubMed1992

[Internal urethrotomy].

Internal urethrotomy is the first treatment for all kinds of urethral strictures except meatal stenosis and complete urethral obstruction. After urethrotomy a urethral catheter is left indwelling for up to 3 days if the urine is already sterile. In the case of infection it remains in place for 2 weeks. Long-term results depend mainly on the extent of periurethral fibrosis. The over-all success rate is about 50%. Only in a few cases can a second or third urethrotomy be definitively curative. Further urethrotomies are clearly only a palliative treatment of the stricture, comparable in effect to repeated urethral dilatation.

Cicatrix↗
PubMed1978

[Indirect lymphography of the urinary bladder in animal experiments (author's transl)].

Of three contrast media injected interdigitally and submucosally as well as instilled into the bladder, Lipiodol UF (particle size of over 15 micron) and the experimental compound AG 52-315 were not resorbed. Another experimental compound (AG 60-99) with an iodine content of 20% and a particle size of ca. 3,5 micron produced, when injected interdigitally, good contrast of the popliteal lymph nodes in all cases (n = 5). Instillation of the same contrast medium into the bladders of five dogs yielded subdued contrast of the paravesicular lymph nodes in one case. Of still another five animals, two showed contrast of the inner iliac lymph nodes after submucosal infiltration of the bladder mucosa with AG 60-99. In all cases (n = 15) inflammatory reaction with necrotic formations were observed. Resorption of the contrast medium was accomplished by heating at 39 degrees C, and was not improved by addition of Hyaluronidase. Because of the low local tolerance of the contrast medium preparation, this successful experiment in indirect lymphography of the urinary bladder of animals cannot be applied clinically.

Animals↗
PubMed1978

[Influence of leakage of the bladder mucosa on the results of external ureterovesicoplasty (author's transl)].

The significance for the results of external ureterovesicoplasty of damaging the vesical mucosa was investigated in rabbits. On one side, the submucosal ureter was lengthened by myotomy, and on the other side, an additional incision of the mucosa caused the ureter to be shifted intravesically. In 10 animals, results were symmetric; in 7 cases, stasis occurred on the side of the sunken ureter; 2 animals showed marked hydronephrosis on the Grégoir side. Increased mobility and thereby kinking of the intravesical ureter and inflammatory reaction on temporary leakage of urine are shown to be the causes of worse results following mucosa leakage. As consequence of the study importance of careful closure of any mucosal defect occurring during Grégoir operation is stressed.

Animals↗
PubMed1978

Internal ureteropexy: a simple technique to prevent reflux after ureteroneocystostomy.

An experimental study in dogs showed that the implantation of hydroureters onto a denuded area of the bladder muscle led to mucosal regeneration and formation of a submucosal tunnel. Reflux was prevented in all animals when the bladder wall was immobilized at the reimplantation site by fixation to the psoas muscle. Urinary stasis normalized after 10 to 12 reimplantations. Internal ureteropexy would seem to be a most simple and satisfactory technique for preventing reflux when dissection of a submucosal tunnel fails in ureteroneocystostomy. It has been used in three patients with good results.

Animals↗
PubMed1977

Ureteroneocystostomy without dissection of the submucosal tunnel.

A technique of ureteroneocystostomy with fixation of the ureter to the bladder musculature denuded from the mucosa was studied in dogs. The intravesical portion of the ureter shrank to half its original length after the operation. This portion preserved its muscular structure and was overgrown by the bladder mucosa to more than half its circumference. The submucous canal thus formed for the ureter prevented reflux in every animal. The technique avoids the formation of strictures. It is recommended if direct dissection of a submucous canal is impracticable.

Animals↗
PubMed1976

[Serum acid phosphatase levels following prostatic massage (author's transl)].

We find an elevation of serum acid phosphatase levels 5 min after prostatic massage in only 10% of patients with prostatic adenoma. This increase is caused by stored prostatic secretion being pressed into the blood vessels. 60 min later these serum levels decrease. With some other patients a slower increase of phosphatase levels occurs; this increase, however, lasts for hours. This kind of increase is caused by prostatic fluid being forced into the interstitium where it is slowly absorbed. A combination of both kinds leads to a curve with two peaks; this could be demonstrated in two cases. No difference was seen in reaction of total acid phosphatase and prostatic phosphatase levels. The increase of phosphatase levels following prostatic massage was no sign of prostatic carcinoma.

Acid Phosphatase↗
PubMed1975

[The position of the renal pelvic axis in the infant (author's transl)].

The position of the longitudinal axis of the renal pelvic system is of special significance in the diagnosis of renal pelvic reduplications, horseshoe kidneys and space occupying processes of the kidney. The present study of 143 normal infant urograms shows that the angle between the axis of the renal pelvis and the axis of the vertebra is dependent on age. While in the newborn a negative angle is a common finding, during adolescence the axis approaches the position we usually find in the adult.

Adolescent↗
PubMed1975

[Perineal and transrectal needle biopsy of the prostate (author's transl)].

On 254 biopsies of the prostate with the tru-cut needle the approach was either rectal or perineal depending on even or uneven dates of birth. The rectal approach showed wrong negative results a little more frequent than the perineal approach. Feverish complications were 6 times more often by rectal than by perineal approach. Additionally the rectal biopsy was complicated by serious bleedings out of the hemorrhoidal vessels or periprostatic veins. Based on the investigations you should chose the perineal approach as the routine method and use the rectal biopsy only for special indication.

Adult↗