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Biomedical subjects

R Chmiel

Publications and source records attributed to R Chmiel.

26 records · Page 2Linked to original sources

Identification of the site of severe colon bleeding by technetium-labeled red-cell scan.

In cases of severe colon bleeding, it is more important to know the site than the cause, in case surgery is required. Technetium-labeled red-cell scan (TLRCS) is known to identify the site of bleeding at the rate of 0.1 ml per minute or more. The aim of this retrospective study was to see whether TLRCS was a reliable indicator of the site of severe colon bleeding. A retrospective study was made of patients investigated in this way for acute, severe colon bleeding at St. Vincent's Hospital, Melbourne, from 1984 to 1988 (five years). TLRCS identified the site of bleeding in less than half of the cases but correctly identified the site in all nine patients in whom bleeding was so severe as to require emergency surgery, avoiding total colectomy in eight cases.

Aged↗

Speech tracking in the evaluation of a multichannel cochlear prosthesis.

Individual speech tracking data were analyzed in relation to other variables in 11 adult users of the Nucleus multichannel cochlear implant. Patients were categorized according to postoperative speech tracking results. The resultant groups could also be differentiated on the basis of postoperative MAC scores, surgeon's rating of overall success, and duration of deafness before implantation. The speech tracking paradigm appears to be a useful technique for the evaluation of performance with a cochlear prosthesis.

Adult↗

Rate and filter dependence of the middle-latency response in infants.

Auditory evoked-potential activity in the 0 to 100-ms latency range was explored using wide-band filtering and a range of stimulus rates, in 8 babies ranging in age from 2 to 6 months. We observed both a stable early positive peak, in the 10 to 15-ms region, and a rate-dependent, positive peak at about 50 ms in all 8 babies. The latter response was best observed at rates of 1-2.5 stimuli/s and seldom observed at rates above 4/s. This peak may represent a developmentally early version of the Pa peak of the adult middle-latency response.

Auditory Perception↗

Effect of sleep on the auditory steady state evoked potential.

The effects of both natural and sedated sleep on the auditory steady state evoked potential (SSEP) were evaluated in nine normal-hearing subjects. Both absolute amplitude and phase variability measures were obtained by Fourier analysis of successive samples of the averaged SSEP waveform. Amplitude decreased significantly in the sleeping state but phase variability was not substantially altered. Because it does not seem to be affected by sleep, phase variability of the SSEP is suggested as a potentially useful technique for predicting threshold sensitivity.

Adolescent↗

Renal impairment and its reversibility following variable periods of complete ureteric obstruction.

There is debate concerning the time course and degree of recovery possible after relief of complete unilateral ureteric obstruction. This study in dogs investigates these features. One ureter was occluded for varying periods, and then reimplanted into the bladder. Recovery was monitored by Tc-Sn-labelled diethylene triamine penta acetic acid (D.T.P.A.) scans and renograms together with creatinine clearance studies. The morphological changes were also studied. There was found to be a progressive loss of functional recovery with increasing periods of obstruction, though this was dramatically improved by contralateral nephrectomy once recovery had stabilized. Increased radial scarring developed in the kidney following increasing periods of obstruction.

Animals↗

Detection of deep venous thrombosis by scanning of 99mtechnetium-labelled red-cell venous pool.

A comparative study of 32 patients with suspected deep venous thrombosis was carried out using blood-pool radionuclide scanning and conventional x-ray phlebography. Results of the two methods showed close agreement, the sensitivity (positive correlation) of the scan being 100% and its specificity 89%. We conclude that a patient's red cells labelled with 99mtechnetium (99mTc) provide an excellent medium for this type of scanning. The technique has particular advantages in visualising the whole venous system, giving a persisting image, and obviating the need to inject into a vein of the affected limb. In view of the inherent disadvantages of contrast phlebography, 99mTc-red-cell scanning is clearly an acceptable alternative.

Erythrocytes↗

Twin study of central auditory processing disorder.

We compared auditory, cognitive, and language test results in a pair of dizygotic twins, one of whom showed symptoms of central auditory processing disorder (CAPD). Results highlight the importance of testing binaural function. In particular, electrophysiologic measures of dichotic listening effectively demonstrated the auditory-specific nature of this child's listening problems. The importance of a thorough and comprehensive evaluation of children suspected of CAPD is stressed.

Audiometry, Pure-Tone↗