Biomedical subjects

R Chodos

Publications and source records attributed to R Chodos.

3 recordsLinked to original sources

PubMed1981

Noninvasive evaluation of mediastinal metastases in bronchogenic carcinoma: a prospective comparison of chest radiography and gallium-67 scanning.

Evaluation of regional node involvement in patients with bronchogenic carcinoma is a crucial step in determining therapy and prognosis. Mediastinoscopy has been recommended for staging all potentially operable cases, but technical limitations and the need for anesthesia make this impractical. Gallium-67 scanning and chest radiography were prospectively compared as noninvasive means of evaluating spread to regional nodes in 75 patients with bronchogenic carcinoma in whom histologic evaluation of hilar and mediastinal nodes was performed. Gallium scanning was more accurate than chest radiography in assessing regional nodes (overall accuracy 85.3% vs. 56%, P less than 0.05). When positive, both procedures correctly indicate malignant involvement of regional nodes (85% vs. 87.3%). A negative gallium scan, however, was significantly more accurate in predicting the absence of such involvement (80% vs. 40%, P less than 0.01). Gallium scanning appears to be a reliable, noninvasive means of assessing mediastinal spread of bronchogenic carcinoma and when used in conjunction with radiographic findings, allows selection of appropriate patients for surgical staging procedures.

False Negative Reactions↗

PubMed1978

A comparison of administering protein alone and protein plus glucose on nitrogen balance.

It has been suggested previously that in the fasting state the administration of amino acids alone would be more effective in sparing protein than the administration of amino acids plus small amounts of glucose. In the present study we have examined the effect of administration of amino acids alone (1 g/kg per day) and of the same regimen supplemented with 100 g glucose daily, on the nitrogen balance in 10 subjects, six of whom were obese and four undernourished. Mean cumulative nitrogen balance over a 5-day study period was -12.4 g on amino acids alone and +0.5 g when glucose was added (P less than 0.01). It thus appears that the addition of glucose may be beneficial rather than harmful in subjects receiving amino acid therapy.

Adult↗

PubMed1978

Hemiparetic seizures.

In three patients hemiparesis was a manifestation of focal seizures. In all, there were electroencephalographic abnormalities and radionucleotide uptake in the contralateral hemisphere. Treatment of the seizures resulted in clearing of both paralysis and abnormal brain scan. These patients fit the diagnostic category described by Higier as a "paralytic equivalent of epilepsy without disturbance of consciousness in the form of status hemiparalyticus," and described by others as inhibitory seizures or partial seizures with subsequent hemigeneralization. The etiology of the paralysis and its relation to Todd paralysis are not clear, but it may result from excessive inhibitory discharge.

Child↗