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Biomedical subjects

R Claude

Publications and source records attributed to R Claude.

At least 37 records · Page 2Linked to original sources

[Study of insulin secretion in chronic pancreatitis].

17 oral glucose tolerance tests with simultaneous estimation of plasma insulin, were carried out in 15 patients with chronic pancreatitis of which 7 were of calcific type. Among these patients, 10 had obvious diabetes and 3 chemical diabetes. The disorders of glucose regulation were more common in the calcific form of the disease. Serum insulin was then lower and not stimulant. The curves of plasma insulin obtained in non-calcific pancreatitis were variable. In hyperinsulinism, the oral glucose tolerance test showed flat or normal curves. In hypoinsulinism, the glucose tolerance tests were either normal or strongly pathological. This insulinism, as shown by this study of chronic pancreatitis, seems to be linked to an imbalance in the cell distribution of the islets of Langerhans. The role of glucagon appears preponderant.

Administration, Oral↗

[Proctology].

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Colorectal Surgery↗

[Functional renal failure (FRF) in cirrhosis (author's transl)].

Frequent complication of advanced cirrhosis, spontaneous or in response to different causes, FRF is chiefly characterized by hyponatraemia, progressive azotaemia, hyperkalaemia and severe oliguria. Its functional nature is proved but its mechanism remains doubtful: it may be due to decreased "effective" plasma volume or renal arteriolar constriction. Its treatment is disappointing and in spite of new technics, gives only transitory improvements.

Hemodynamics↗

[The value of ultrasound-guided cyto-biopsy in the study of livers with abnormal ultrasonograms].

This retrospective study considers the diagnostic reliability of 97 cyto-biopsies performed with a fine needle and guided by ultrasonography in 92 patients with one or several suspicious liver lesions. The results of the cyto-biopsy were compared with the final diagnosis obtained by histological examination or by the evolution. In 65 confirmed malignant tumors, fine needle biopsy was concordant in 54 cases. The sensitivity of this method in the diagnosis of malignant liver lesions was 83% with a specificity of 93%. In 54 malignant cytologies, the differentiation between primary or secondary lesions was possible in 31 cases (57%). In 32 confirmed benign lesions, fine needle biopsy was concordant in 30 cases. This study confirms the advantage of cyto-biopsy guided by ultrasonography in the positive and etiological diagnosis of malignant liver tumors.

Adult↗