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Biomedical subjects

R Clement

Publications and source records attributed to R Clement.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Nycthemeral blood pressure monitoring in the diagnosis of borderline arterial hypertension in young adults].

PURPOSE: Evaluating Blood Pressure Monitoring contribution at rest to the diagnosis and pathophysiology of borderline (BL) hypertension in the twenties. METHOD: a nycthemeral blood pressure recording each 15 minute has been performed during the 48 first hours of hospitalisation on two groups of white twenties males with a Dinamap: 143 CONTROLS. Mean age: 21.1 +/- 2 yrs, mean height: 177 +/- 7 cm, mean weight: 71 +/- 11 kg; 104 BL hypertensive patients. Mean age: 21 +/- 2 yrs, mean height: 178 +/- 7 cm, mean weight: 78 +/- 12 kg. Mean BP recording levels are smaller than casual measurements in two groups: CONTROLS (Casual BP: 125/71, BP recording on 24 hours: 117/60, day time: 121/63, nighttime: 110/54 mmHg). BL hypertensives (Casual BP: 144/83, BP recording on 24 h: 132/69, daytime: 137/73, nighttime: 121/60 mmHg). Nycthemeral BP variability measured by the standard deviation of mean pressure is not different in two groups for systolic variability, it significantly differs for diastolic variability (BL: 7.6/CONTROLS: 5.5, p less than 0.01). Correlations between casual BP and diurnal records are stronger in controls than in BL patients showing a lower predictive value of clinical assessment in BL patients. Though the same heart rate at sleep, BP is significantly higher in BL than in controls. It probably means that factors different from sympathetic activity are involved in pathophysiology of borderline hypertension. The whole measurement study on 24 hours of two groups show an important overlap (the 65th percentile in BL systolic BP correspond with the 95th of controls, the 74th percentile in BL diastolic BP correspond with the 95th in controls). That make difficult the recording evaluation for a given patient.

Adult↗
PubMed1986

Operative and nonoperative treatment of mallet finger.

Forty-four patients with 47 mallet fingers were reviewed to compare the results of operative (24 fingers) and nonoperative (23 fingers) treatment. Distal interphalangeal (DIP) joint extension, DIP flexion, total active motion of the DIP joint, proximal interphalangeal (PIP) extension, PIP flexion, total active motion of the PIP joint, cold intolerance, and persistent pain after treatment were not significantly different in patients treated by surgery or splinting. Secondarily, we compared fingers with and without a fracture of the distal phalanx, and the variables mentioned above were also unaffected by the presence or absence of fractures of the distal phalanx. About one-third of all patients had decreased PIP joint motion following treatment. In about 16% of all patients this loss of PIP motion was more important in determining finger function than DIP motion or symptoms related to the DIP joint. We recommend careful examination of the PIP joint and repeated monitoring of the joint motion. If the PIP joint becomes stiff, therapy and splinting should be used to minimize permanent stiffness. We believe a prospective randomized comparison of operative and nonoperative treatment of mallet finger should be conducted. Such a study would help determine the ideal treatment for mallet finger.

Exercise Therapy↗
PubMed1982

[Exercise-induced malignant hyperthermia in a patient with familial ichthyosis vulgaris. Muscular carnitine deficiency as contributing factor (author's transl)].

A young soldier with familial ichthyosis vulgaris developed malignant hyperthermia after an intensive exercise. Ichythyosis was considered as a predisposing factor, but the finding of a low muscular carnitine level raises the problem of a relationship between exercised-induced malignant hyperthermia and lipid metabolism disorders.

Adult↗
PubMed1979

[Experimental study of vibrio parahaemolyticus (biotype 2) transfer from water and sediments to benthic marine food chain organisms].

Transfer of Vibrio parahaemolyticus (biotype 2) from sediments to water and from water to benthic marine organisms was studied experimentally using a streptomycin-resistant strain. Transmission by trophic pathways was also studied using reconstituted marine food chains (Mytilus edulis, Nereis diversicolor, Carcinus maenas, Scorpaena porcus, Mus musculus). Water colonization by sediments could be observed only at temperatures above 16 degrees C. Sediments could well constitute a disseminating reservoir for these germs, their cycle in water being dependent of the cycle followed in the sediments. Contamination of animal organisms is essentially effected by a direct mean, either water or sediments; transfer by trophic pathways being negligible. Infection of land consumers (mice) is linked quantitatively to the nature of the last marine organism of the food chain since bacteria can flourish in the digestive tract of certain animals (Carcinus maenas).

Animals↗
PubMed1979

[The value of tomodensitometry in the treatment of carcinoma of the uterus (author's transl)].

The authors performed pelvic and lumbo-aortic tomodensitometry (TDM) in 67 patients with invasive carcinoma of the cervix. Localisation of the cervix is aided by the insertion of a vaginal marker and by opacification of the bladder and rectum. The density and appearance of tumour tissue are identical to those of normal uterine muscle. Under such conditions, TDM is of no use in seeing partial or total involvement of the cervix without any increase in cervical size. TDM gives a clear picture of hypertrophic neoplastic cervices and may be used to obtain exact measurements. TDM offers valuable information in cases of spread to the parametrium, lymphadenopathy or visceral metastases. During radium therapy, TDM shows the relationships between the radioactive sources and the centri-pelvic tumour. It facilitates the drawing of isodose curves. TDM is not a method suitable for the early diagnosis of carcinoma of the cervix. It adds very useful complementary information to clinical examination and classical investigation.

Female↗
PubMed1977

Spatial frequency and orientation tuning curves of visual neurones in the cat: effects of mean luminance.

Experiments have been performed on unanaesthetized and paralysed cats. The tuning curves for spatial frequency of retinal, lateral geniculate and simple and complex cells of the cortex have been determined in response to sinusoidal gratings of various spatial frequencies at different levels of mean luminance. For all neurones, decreasing the mean luminance leads to a progressive loss of spatial resolution and contrast sensitivity. Retinal ganglion cells of type X show, for scotopic levels of luminance, a flattening of their spatial frequency tuning curves in the low spatial frequency range. For geniculate and cortical neurones, on the contrary, the spatial frequency characteristics at the various levels of luminance remain practically invariant in their bandwidth. On the average, complex cells still respond to mean luminances ten times lower than simple cells. The tuning curves for orientation of cortical cells maintain, to a first approximation, the same shape at the various levels of mean luminance. The results are discussed comparing the electrophysiological with psychophysical data.

Animals↗
PubMed1975

Binding of lactose repressor to poly d(A-T) : OD AND CD melting of the complex.

The binding of lactose repressor to poly d(A-T) at low ionic strength has been investigated by heat denaturation. The poly d(A-T) melting is monitored by optical density and the protein melting by circular dichroism. From the modification of the poly d(A-T) melting curve we estimate a maximum binding ratio of about one tetrameric repressor to about 20 basic pairs. The repressor melting can be interpreted as a global shift from a to b structure of about 25 residues per subunit. The melting curves of poly d(A-T) and repressor have not a shape easy to interpret; nevertheless both show a cooperative transition in the same temperature range where we can evaluate that about 3.8 aminoacid residues shift from a to b structure when 1 bases pair melt.

Adenine Nucleotides↗