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Biomedical subjects

R Colović

Publications and source records attributed to R Colović.

At least 73 records · Page 4Linked to original sources
PubMed1980

Some experimental aspects of using lungs as biological oxygenator in extracorporal circulation.

Exposing problem of oxygenators in extracorporal circulation authors consider screen and membrane as the best, in spite of some disadvantages from which the haemolysis is the most cumbersome. In attempt to find the way of solution of this problem, authors have made a number of experiments in animals where they have conducted extracorporal circulation in such way that blood has been oxygenated in own lungs of an animals. Two types of bypass were examined as: right to right bypass (vv. cavae-pulmonary artery), right to right bypass as exposed with possibility of interconnection with classical extracorporal circulation, and finally bypass of the left and right heart. Exposing their experience and results authors consider that use of lungs as biological oxygenator in extracorporal circulation has its justification according to achieved results. In spite of some problems which need further elaboration such experiments are the motive for more work and reflexion in this type of problem.

Animals↗
PubMedDate not supplied

[Giant epithelioid leiomyosarcoma of the stomach].

Epithelioid leiomyosarcoma of the stomach is an uncommon tumour, predominantly in old persons. The majority of tumours are small, giant tumours are rare. A tumour is more frequent in the upper part of the stomach. It rarely gives secondary deposits, almost only large ones. In a few big published series of patients, secondary deposit were not found in lymph nodes or other organs. Gastrointestinal bleeding, easy fatigue and pain are the usual symptoms of the disease. Endoscopic and fine needle biopsy was successful in single cases. A limited wedge gastric resection is considered as one of the most appropriate surgical treatments. Major resections are reserved for giant tumours infiltrating surrounding organs, and for recurrencies. Due to rare involvement of lymph nodes, systematic lymph node dissection is not regarded as a necessary procedure. The recurrencies can be successfully removed in a number of cases. Chemo- and radiotherapy are generally regarded as useless. We present a 61-year old male patient who had discomfort in the upper abdomen. CT scan was performed but radiologist missed to diagnose an obvious mass in the upper mid-abdomen. Three years later he came with high temperature and leukocytosis. The preoperative examination showed conflicting results, ultrasonography that the tumour did not belong to the liver but CT scan showed that the tumour arose from the left lobe of the liver. Barium swallow showed signs of external pressure on the stomach from the right toward left and downwards. During the operation, a giant gastric tumour (215 x 139 x 135 mm) originating in the antral part of the small gastric curvature was removed with distal 2/3 of the stomach. Histologic examination showed epithelioid leiomyosarcoma of the stomach with umbilical ulceration. About 50% of the tumour was necrotic. There were no lymph node deposits. Temperature and WBC count dropped to the normal value soon after surgery. The patient stayed symptom-free so far, five months after the operation.

Humans↗
PubMedDate not supplied

Isolated hydatid cyst of the adrenal gland.

Hydatide disease of the adrenal gland is extremely rare, even in disseminated disease. Isolated cyst of the gland is even more rare. Only 9 of such cases seem to have been described so far. We present a 49 year old woman in whom a hydatide cyst of the right gland was found during the investigation for the dull pain in the area. She was successfully operated. Hydatide etiology was confirmed at operation and by histology. She had an uneventful recovery. The preoperative pain disappeared postoperatively.

Adrenal Gland Diseases↗
PubMedDate not supplied

[Mesenteric lipoma causing volvulus of the small intestine].

Volvulus of the small bowel is not so frequent as is volvulus of the colon. A delayed diagnosis and surgical treatment result in high rate bowel infarction which can lead to perforation and stercoral peritonitis. If perforation does not take place, the infarcted bowel has to be resected causing multiple complications and mortality. The small bowel volvulus is caused by mesenteric lipoma in about 5% of cases. We present a 77-year-old man operated on for intestinal obstruction. The patient was admitted in a serious condition with a five-day history of abdominal pain and vomiting. On admission he vomited a small bowel content (miserere), he was dehydrated and with high blood urea and creatinine values. Plain X-ray showed a number of air fluid levels in the small bowel. At operation a small bowel volvulus caused by mesenteric lipoma (18 x 11 x 10 cm in diameter) with bowel infarction but without free perforation and peritonitis, was found. The tumour was removed together with 10 cm of resected bowel with end-to-end anastomosis. The recovery was uneventful. The patient is still symptom free.

Aged↗
PubMedDate not supplied

[Hamartoma of the spleen].

Hamartoma is a rare benign lesion of the spleen. Between 140 and 150 cases seem to have been described so far. Hamartoma of the spleen may appear as a single or multiple lesions which may tend to converge. It appears in all ages, mainly in elderly persons. About 20% of patients were described in paediatric subjects. Half of the patients have no symptoms, so that hamartomas were discovered by chance at autopsy. Other 50% of patients had pain, splenomegaly, haematologic abnormalities (most frequently thrombocytopenia or pancytopenia) and spontaneous rupture with intra-abdominal bleeding. In children, hamartoma of the spleen with haematologic abnormalities may be followed by growth retardation, frequent infections, fever and night sweating. The bigger the hamartoma the greater probability to cause symptoms. The exact preoperative diagnosis is rarely established. Hamartoma has to be taken into account always when tumour of the spleen is diagnosed, particularly in children. Splenectomy is the most frequent treatment of symptomatic hamartoma of the spleen. Partial splenic resection is the preferred surgery whenever it may be carried out, particularly in children. We report a 58 year old woman with a five-year history of left subcostal and lumbar pain in whom in the lower pole of moderately enlarged spleen a tumorous mass, 107 x 75 mm in diameter, was discovered on ultrasonography. She was submitted to splenectomy as well as to cholecystectomy due to gall bladder stones. Histological findings of the spleen showed hamartoma. She had an uneventful recovery. The pain disappeared after surgery. She stayed symptom free so far.

Female↗
PubMedDate not supplied

[Solid and cystic-papillary tumor of the pancreas].

Solid and cystic-papillary tumour of the pancreas is a rare neoplasm. About 420 cases seem to have been reported as yet. It appears almost exclusively in young women, although it may appear in males in all ages. This is a tumour of benign or low malignant potential with vary rare invasion of surrounding tissues and organs. Metastases of the tumour are rare. Local recurrence after surgical excision is also rare. About 50% of patients have no symptoms. The others may have upper abdominal pain or palpable abdominal mass. Complications such as rupture, bleeding or secondary infection, are rare. The average size of the tumour is cca 10 cm in diameter. The tumour is more frequent in the body and tail of the pancreas. New imaging techniques make diagnosis of the tumour very easy, but exact diagnosis is based on histological findings. Surgical excision is the treatment of choice. We report on a 23-year-old woman with a two-year history of upper abdominal pain and occasional fever, in whom ultrasonographic and CT scan examinations revealed a well defined mass of 5 cm in diameter. The mass was excised with limited resection of the pancreas along with removal of the spleen which was adherent to the mass so that it could not have been saved. Histological findings established a solid and cystic-papillary neoplasm of the pancreas. The recovery was uneventful. The patient was symptom-free, with normal clinical findings and laboratory results.

Adult↗