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Biomedical subjects

R D Beckenbaugh

Publications and source records attributed to R D Beckenbaugh.

At least 19 recordsLinked to original sources
PubMed2003

[Arthroplasty of the metacarpophalangeal joint using pyrocarbonate implants].

As early as the 1970s, pyrocarbon became a point of focus in the search for materials for alternative finger replacement. This type of material had already proven its biocompatibility and excellent wear behaviour in its use for artificial heart valves. The first trials with pyrocarbon surface replacement implants for the small finger joints in baboons showed good biocompatibility as well as good functional results. The first patient series confirmed theses results in long-term follow-up. Meanwhile, the surface replacement implants made of pyrocarbon are an interesting alternative to silicon spacers. Further developments for other joints in the hand are under evaluation.

Arthritis, Rheumatoid↗
PubMed2001

Long-term results of cemented Steffee arthroplasty of the thumb metacarpophalangeal joint.

A retrospective evaluation of the Steffee metacarpophalangeal (MCP) thumb joint prostheses was performed to determine the long-term outcome and survivorship of the prosthesis. Fifty-four primary thumb arthroplasties (49 patients) were performed for pain, weakness, or instability involving the thumb MCP joint secondary to arthritis. Underlying etiology included rheumatoid (49 thumbs), psoriatic (1 thumb), scleroderma (2 thumbs), and degenerative (2 thumbs) arthritis. Thirty-one thumbs had concomitant interphalangeal joint instability and underwent interphalangeal joint fusions. At an average follow-up period of 57 months, the average motion of the MCP joint was 21 degrees (range, 0 degrees to 40 degrees ), with a significant improvement in position and stability. Thumb axis length was maintained or increased in 98%. Although there was not a consistent long-term improvement in grip or pinch strength, 87% of the patients reported subjective improvement in strength and function as a result of surgery. Pain was relieved in all thumbs with preoperative pain. Complications included a periprosthetic fracture, 2 late infections, and 1 gross loosening of the implant. The survivorship of the implant was 93% survivorship at 5 years and 89% survivorship at 10 years, with only 4 failures in 54 thumbs. The Steffee thumb MCP arthroplasty resulted in excellent long-term survivorship, patient satisfaction, and functional outcome.

Adult↗
PubMed1999

Long-term follow-up of pyrolytic carbon metacarpophalangeal implants.

BACKGROUND: The metacarpophalangeal joint is the most commonly involved joint when rheumatoid arthritis affects the hand. Many prosthetic implants have been designed for the replacement of this joint. Although studies of these implants have shown relief of pain, they have generally demonstrated a poor range of motion, progression of ulnar drift, and bone loss, as well as failure, fracture, and dislocation of the implant. METHODS: From December 1979 to February 1987, 151 pyrolytic carbon metacarpophalangeal implants were inserted in fifty-three patients. The implants had an articulating, unconstrained design with a hemispherical head and grooved, offset stems. Forty-four patients had rheumatoid arthritis; five, posttraumatic arthritis; three, osteoarthritis; and one, systemic lupus erythematosus. Three patients (eleven implants) were lost to long-term follow-up, and twenty patients (fifty-one functioning implants) died after the implant had been in situ for an average of 7.2 years. Eighteen implants (12 percent) in eleven patients were revised. Fourteen of the eighteen implants were replaced with a silicone-elastomer or another type of implant, and the remaining four were removed and a pyrolytic carbon implant was reinserted with the addition of bone cement or bone graft, or both. Twenty-six patients (seventy-one implants) were available for long-term review at an average of 11.7 years (range, 10.1 to 16.0 years) after implantation. RESULTS: The implants improved the arc of motion of the fingers by an average of 13 degrees and elevated the arc by an average of 16 degrees. As a result, fingers were in a more functional, extended position. A complete set of preoperative, postoperative, and follow-up radiographs was available for fifty-three of the seventy-one implants that were followed long term. There was a high prevalence of joint stability: fifty (94 percent) of the fifty-three implants were in a reduced position postoperatively, and forty-one (82 percent) of those fifty implants were still in the postoperative reduced position at the time of long-term follow-up. Ulnar deviation averaged 20 degrees preoperatively and 19 degrees at the time of follow-up, with only the long finger having an increase in deviation. No adverse remodeling or resorption of bone was seen. Fifty (94 percent) of the fifty-three implants had evidence of osseointegration, with sclerosis around the end and shaft of the prosthetic stems. Radiolucent changes were seen adjacent to twelve implants. There was minimum-to-moderate subsidence (four millimeters or less) of thirty-four implants; most of the subsidence occurred immediately postoperatively. Survivorship analysis demonstrated an average annual failure rate of 2.1 percent and a sixteen-year survival rate of 70.3 percent. The five and ten-year survival rates were 82.3 percent (95 percent confidence interval, 74.6 to 88.2 percent) and 81.4 percent (95 percent confidence interval, 73.0 to 87.8 percent), respectively. None of the revised implants had any visible changes of wear or deformity of the surfaces or stems. Four instances of chronic inflammatory tissue and three instances of proliferative synovitis were noted histologically. Focal pigment deposits were seen in three fingers, one of which had removal of the implant two months after a fracture. No evidence of intracellular particles or particulate synovitis was found. CONCLUSIONS: The results of this study demonstrate that pyrolytic carbon is a biologically and biomechanically compatible, wear-resistant, and durable material for arthroplasty of the metacarpophalangeal joint.

Arthritis, Rheumatoid↗
PubMed1997

Trispiral tomographic staging of Kienböck's disease.

Trispiral tomography enhances the staging of Kienböck's disease and aids in surgical planning. The clinical records, plain x-rays, and trispiral tomograms of 105 patients with Kienböck's disease were reviewed. When tomograms were used, upward revision of the classification stage was indicated in 73% of patients with stage I or stage II disease and in 10% of those with stage III disease. On tomograms, 91% of patients had lunate fractures, compared with 55% on plain films. The most common lunate fracture seen on trispiral tomograms was a transverse shear fracture that represented lunate collapse; the next most common was a midcoronal fracture that may be displaced, causing fragment extrusion palmarly or dorsally. The most common instability pattern was nondissociative proximal row flexion, seen in stage III. Indices of carpal collapse and ulnar translation may be useful in following up patients, but values vary widely among patients.

Adolescent↗
PubMed1997

Development of a surface replacement arthroplasty for proximal interphalangeal joints.

Sixty-six surface replacement proximal interphalangeal prostheses with a CrCo proximal and an ultrahigh-molecular-weight polyethylene distal component were used in the hands of 47 patients (mean age, 58 years) over a 14-year period. There were 37 fingers with degenerative arthrosis, 16 with traumatic arthrosis, and 13 with rheumatoid arthritis. The mean follow-up period was 4.5 years (range, 1-14 years). The results based on pain relief, motion, and deformity were good in 32 fingers, fair in 19, and poor in 15. Poor results occurred primarily in fingers with previous extensive injury or static deformity. Results with a dorsal approach were better than those with a lateral or palmar approach. Component loosening at the bone-cement junction beyond a minimal radiolucent line was seen in one late x-ray. Results in individuals changed little after the first year of follow-up care, but results overall improved during the course of the study, perhaps because of improvements in surgical technique and experience.

Adolescent↗
PubMed1997

Tissue cytokine patterns distinguish variants of rheumatoid synovitis.

Rheumatoid arthritis (RA) is a chronic inflammatory disease with primary manifestations in the synovial membrane. Tissue infiltrates are composed of T cells, B cells, and macrophages, but histopathological appearances vary widely and are rarely pathognomonic. Mechanisms underlying the phenotypic heterogeneity of rheumatoid synovitis are not known. To explore whether a correlation exists between the microscopic patterns of rheumatoid synovitis and in situ production of cytokines, tissue samples from 21 consecutive patients with clinically active RA were examined. Based upon the organization of the lymphocyte infiltrate, the synovial biopsies were categorized into three distinct subsets. Ten samples were characterized by diffuse lymphoid infiltrates without further microarrangement. In seven samples, lymphoid follicles with germinal center formation were detected, and in four specimens, granuloma formation was identified. In all specimens, cytokine transcription of interferon (IFN)-gamma, interleukin (IL)-4, IL-1 beta, tumor necrosis factor (TNF)-alpha, IL-10, and transforming growth factor-beta 1 was semiquantified with polymerase chain reaction and liquid phase hybridization. Each of the morphologically defined variants of synovitis displayed a unique cytokine profile. Low-level transcription of IFN-gamma, IL-4, IL-1 beta, and TNF-alpha was typical of diffuse synovitis. In follicular synovitis, IFN-gamma was the dominant cytokine, IL-4 was virtually undetectable, and IL-10 was abundant. Granulomatous synovitis demonstrated high transcription of IFN-gamma, IL-4, IL-1 beta, and TNF-alpha and could be clearly distinguished from the other phenotypes. To investigate whether differences in the synovial lesions were related to host factors, patients were compared for clinical parameters. Diffuse synovitis was seen in most of the patients with seronegative RA, the mildest form of the disease. In contrast, extra-articular spreading of RA with nodule formation was typically associated with granulomatous synovitis. In summary, RA patients display reproducible patterns in the organization and activity of synovial infiltrates. The correlation of microanatomy with tissue cytokine production suggests that several pathomechanisms can modulate the expression of the immune response in the synovial membrane.

Adult↗
PubMed1996

Biaxial long-stemmed multipronged distal components for revision/bone deficit total-wrist arthroplasty.

Revision total-wrist arthroplasty has a high incidence of complications. Loosening is a significant problem for the distal implant. Because of the high failure rate of single-pronged distal implants after revision total-wrist arthroplasty, a custom multipronged distal component (biaxial total-wrist implant) was designed for use in patients with deficient bone stock who undergo revision operation. Ten cases of total-wrist arthroplasty with a custom long-stemmed multipronged distal component are presented. The preoperative diagnosis was failed total-wrist arthroplasty in 9 cases. Mean time from previous total-wrist arthroplasty to revision procedure was 5.6 years. At follow-up evaluation (mean, 3.8 years; range, 3.0-4.8 years), 2 patients had undergone arthrodesis: 1 patient at an outside institution 1 year after surgery for periprosthetic fracture of the radius, and 1 patient at our institution for distal implant loosening. The 8 other patients had functional total-wrist arthroplasties. At follow-up evaluation, all patients reported they were satisfied. Six patients reported no pain and 2 reported mild pain. Mean range of motion at follow-up evaluation was within the previously defined limits that allow patients to function in activities of daily living: 78 degrees for supination, 77 degrees for pronation, 39 degrees for extension, 17 degrees for flexion, 12 degrees for radial deviation, and 18 degrees for ulnar deviation. Revision total-wrist arthroplasty with custom long-stemmed, multipronged distal components offers an alternative to those patients with deficient bone stock who refuse arthrodesis. Early results demonstrate greater longevity compared with single-pronged components for revision total-wrist arthroplasty.

Arthritis, Rheumatoid↗
PubMed1996

Biaxial total-wrist arthroplasty.

Sixty-four consecutive biaxial total wrist arthroplasties performed in 52 patients between March 1983 and June 1988 were reviewed. Fifty-seven cases involving 45 patients were followed for a minimum of 5 years or until failure. Of the remaining 7 patients, 6 had died and 1 was lost to follow-up study. For the 46 intact implants in living patients, the mean follow-up period was 6.5 years (range, 5-9.9 years). The mean patient age at operation was 58 years. The underlying diagnosis was rheumatoid arthritis in 63 cases and juvenile rheumatoid arthritis in 1 case. At follow-up evaluation, pain was reported as none in 75%, mild in 19%, moderate in 3%, and severe in 3%. Patients rated their improvement as much better in 62%, better in 30%, some improvement in 4%, and worse in 4%. Range of motion at last follow-up averaged 36 degree extension, 29 degree flexion, 10 degree radial deviation, and 20 degree ulnar deviation. Grip strength improved from 4.1 kg preoperatively to 5.9 kg at last follow-up evaluation. Pain was likewise significantly improved at 1 year and 5 years. Failures occurred in 11 cases. The causes of failure were loosening of the distal implant in 8 cases and infection, dislocation, and progressive soft tissue imbalance in 1 case each. An abnormal resting stance and distal implant subsidence (> or = to 3 mm) at 1 year were associated with implant failure at final follow-up evaluation. The Kaplan-Meier probability of survival free of revision was 83% at last follow-up evaluation

Adult↗
PubMed1995

Clinical efficacy of electroneurometer screening in carpal tunnel syndrome.

The authors evaluated the motor latency values of 72 median nerves assessed with the compact, hand-held, battery-powered NervePace Electroneurometer. Results of this test were compared to those of clinical examination, standard electrodiagnostic tests, and median nerve findings of compression at the time of surgery in 23 patients. The motor latency values obtained with an electroneurometer correlated positively with those from routine electromyography (EMG): sensitivity and specificity were calculated for the ability to diagnose carpal tunnel syndrome (CTS) (> 3.9 ms considered abnormal). This study identified a sensitivity of 85.7% and a specificity of 87.5% in predicting CTS, as confirmed by complete EMG and electroconduction studies.

Carpal Tunnel Syndrome↗
PubMed1994

The early history of arthroplasty of the wrist. From amputation to total wrist implant.

During the past 3 decades implant arthroplasty of the destroyed wrist has become a reliable and satisfying procedure. However, the first total wrist replacement was performed in Berlin as early as 1890. This paper describes the history of resection and interposition arthroplasty of the wrist leading to the first total wrist implant arthroplasty performed by Themistocles Gluck. An overview of recent designs is given, and the relevant historical cases are reported.

Amputation, Surgical↗
PubMed1993

Revision total wrist arthroplasty.

Biaxial design total wrist arthroplasty was used to salvage 13 failed total wrist arthroplasties of various designs. After a follow-up period of 31 months, two wrists had undergone further prosthetic revision for loosening and one wrist was arthrodesed. In the remaining 10 wrists, 8 had no pain, 1 had mild pain, and 1 had moderate pain. Eight patients reported feeling much better, one reported feeling better, and one reported no change. Postoperative range of motion averaged 36 degrees of extension, 19 degrees of flexion, 6 degrees of radial deviation, and 15 degrees of ulnar deviation. X-ray films at follow-up evaluation showed that two revision arthroplasties still in place were loose. The majority of patients had a satisfactory clinical result after revision total wrist arthroplasty with a biaxial design. Loosening of the revision is a significant problem.

Arthritis↗
PubMed1990

Proximal radioulnar synostosis after repair of distal biceps brachii rupture by the two-incision technique. Report of four cases.

In four cases, proximal radioulnar synostosis developed as a complication of distal biceps tendon reattachment through a two-incision technique. The synostosis was excised in all four cases but recurred in two. In each case, the initial reattachment exposed the bicipital tuberosity of the radius anteriorly and exposed the ulna extraperiosteally through a second incision along its subcutaneous border. This two-incision approach may place the patient at risk for synostosis. If two incisions are to be used for distal biceps tendon reattachment, then a limited muscle-splitting approach through the extensor muscle mass, which avoids exposure of the ulna, may be preferable.

Adult↗
PubMed1988

Fracture of the hamate hook.

Twenty-one cases of hamulus fracture are presented. Diagnosis depends on clinical acuity. The most common symptom is pain in the palm that is aggravated by grasp. Weakness of grasp and dorsal wrist pain are also common. Ulnar nerve paresthesia or weakness and mild carpal tunnel syndrome are frequently present. Tenderness directly over the hamulus is always present, and grip strength typically is diminished. Tenosynovitis, tendon fraying, or tendon rupture may be demonstrated in 25% of the cases and is not related to the use of steroids. Lateral trispiral tomography is clearly superior to the other diagnostic methods. Excision produced generally excellent results, particularly in patients with an athletic injury or with no associated additional injury. A nonathletic injury or the presence of associated trauma adversely affected results. Immediate immobilization of acute fractures may result in fracture healing and obviate operative intervention. Open reduction and internal fixation is feasible but offers little advantage over excision.

Adolescent↗