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Biomedical subjects

R D Budd

Publications and source records attributed to R D Budd.

At least 19 recordsLinked to original sources
PubMed1989

Drugs of abuse found in fatally injured drivers in Los Angeles County.

Blood or urine specimens from nearly 600 fatally injured drivers in two Los Angeles County studies were analyzed for the presence of alcohol and other drugs of abuse, including PCP, cocaine, opiates and marijuana. The results of the preliminary study indicate that 65 out of 102 fatally injured drivers had used alcohol and/or another drug of abuse - 34 had used alcohol only, 12 had used one or more other drug(s) of abuse, and 19 had used alcohol in combination with another drug of abuse. The results of the larger follow-up study, begun a year later, indicate a continued high level of both alcohol use (41.5%) and marijuana use (19%) with moderate cocaine usage (8%) and low levels (less than 2%) of barbiturate and PCP usage.

Accidents, Traffic↗
PubMed1989

Cocaine abuse and violent death.

One hundred and fourteen Los Angeles County Coroner's cases found to be positive in drug screening for the presence of cocaine were studied to determine the relationship between cocaine abuse and violent death. Of these 114 victims, 70 (61.4%) died a violent death--over 68% of these as shootings and stabbings. Fourteen of the violent death victims (20%) were found to have been behaving in a violent manner just prior to their death. Violence seems to be clearly connected to the use and abuse of cocaine.

Accidents↗
PubMed1983

The determination of cocaine and its major metabolite, benzoylecgonine, in postmortem fluids and tissues by computerized gas chromatography/mass spectrometry.

An analytical procedure for the simultaneous determination of both cocaine and benzoylecgonine in postmortem fluid and tissue samples has been developed by using computerized gas chromatography/mass spectrometry and gas chromatography using a nitrogen/phosphorus (N/P) detector. Both methods are accurate and sensitive and allow the determination of tissue concentrations of cocaine and benzoylecgonine as low as 0.015 microgram/mL.

Autopsy↗
PubMed1982

The incidence of alcohol use in Los Angeles County homicide victims.

The blood alcohol levels were determined in 100 Los Angeles County homicide victims who died in August 1980. A total of 61% had levels of 0.01% or more. Since this percentage is substantially higher than would be expected for a cross section of the population, it appears that alcohol use is one factor that increases the chances of a person becoming a homicide victim.

Adolescent↗
PubMed1982

Phencyclidine concentrations in postmortem body fluids and tissues.

Phencyclidine (PCP) concentrations have been studied in the blood and tissues of Los Angeles County victims whose deaths were related to PCP use. In most cases PCP blood concentrations ranged from 0.01 to 0.9 micrograms/mL while higher concentrations were found in the liver, urine, bile, brain, and kidney.

Adult↗
PubMed1982

Characteristics of victims of PCP-related deaths in Los Angeles County.

The characteristics of the 104 persons who died in Los Angeles County in 1980 where PCP use was involved, have been studied. A majority of these victims were Black (73%), males (85%), in their twenties (20-29 (58%)), and the victim of a homicide (52%). In only 14% of these cases was there a fatal overdose of PCP alone or in combination with other drugs.

Adolescent↗
PubMed1981

Mass screening and confirmation of phencyclidine (PCP) in urine by radioimmunoassay/TLC.

A sensitive, rapid, and specific procedure is described for the mass screening and confirmation of PCP (phencyclidine) in urine specimens at concentrations as low as 0.3 microgram of PCP per mL. Specimens that test positive by radioimmunoassay must be confirmed by TLC using methylene chloride:n-butanol:concentrated NH4OH (85:15:0.5) as the developing solvent system. This separates PCP from other drugs or endogenous urinary substances.

Chromatography, Thin Layer↗