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Biomedical subjects

R D Cooper

Publications and source records attributed to R D Cooper.

At least 73 records · Page 4Linked to original sources
PubMed1985

Orally absorbable cephalosporin antibiotics. 2. Structure-activity studies of bicyclic glycine derivatives of 7-aminodeacetoxycephalosporanic acid.

Three positional analogues (4-, 5-, and 7-) of benzothienylglycine and (N-acetylindolinyl)-5-glycine were prepared and coupled to 7-aminodeacetoxycephalosporanic acid (7-ADCA) to give the cephalosporins 17a-c. In addition two isomeric (2,3-b and 3,2-b) thienothiopheneglycines were synthesized and coupled to 7-ADCA to yield cephalosporins 30d and 30e. In vitro testing of these new cephalosporins indicates good activity against Gram-positive bacteria. Against Streptococcus pneumoniae infections compound 25 displayed better mouse protection (both orally and subcutaneously) than cephalexin.

Administration, Oral↗
PubMed1983

Occupational stress among international interpreters.

In this study the sources of stress among international interpreters were explored. It was found that the major source of job dissatisfaction among interpreters was their perception of their work as noncreative and requiring little initiative. In addition, it was discovered that one of the most important stressors affecting the mental health of interpreters working in international forums was home life problems generated by their work (e.g., frequent traveling, long working hours). The differences between free-lance and staff interpreters were also explored. The implications of the results for the employing authorities are discussed.

Adult↗