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Biomedical subjects

R D Eastham

Publications and source records attributed to R D Eastham.

At least 37 records · Page 2Linked to original sources
PubMed1970

Macrocytosis in Down's syndrome and during long-term anticonvulsant therapy.

In a group of non-anaemic mentally retarded patients a significant increase in mean red cell volume has been demonstrated in epileptic patients being treated with anticonvulsants. The possible sites of interference of anticonvulsants with folate activity in the body, and problems associated with folic acid supplements during anticonvulsant therapy, are discussed. During the survey it was confirmed that the mean red cell volume is abnormally increased in many cases of Down's syndrome.

Adult↗
PubMed1970

The irrelevance of adhesive platelet estimations after thrombosis.

It has been found that adhesive platelet counts are not of clinical use either after surgical operation or during long-term anticoagulant therapy in the detection of thrombosis. Calculation of the theoretical risk of development of platelet thrombi related to the platelet count suggests a possible reason for this absence of clinical significance. The evidence that platelet adhesiveness alters because of uncontrollable platelet variables and is controlled at least in part by plasma factors is discussed. The possibility of measuring the plasma factors is considered briefly.

Adenine Nucleotides↗