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Biomedical subjects

R D Finlay

Publications and source records attributed to R D Finlay.

6 recordsLinked to original sources
PubMed2000

Sub-Tenon's local anaesthesia: the effect of hyaluronidase.

AIMS: A prospective, randomised, double blind study was used to investigate the effect of hyaluronidase on the quality of block achieved with sub-Tenon's local anaesthesia. METHODS: 150 patients scheduled for elective cataract surgery were randomly allocated to either sub-Tenon's block with 3 ml lignocaine 2%/adrenaline 1:200 000 alone or with the addition of 30 IU/ml of hyaluronidase. The blocks were assessed for degree of akinesia and reduction of eyelid movement, and also post-injection and postoperative pain scores. RESULTS: Akinesia and reduction of eyelid movement measured 10 minutes after injection were significantly better in the group with hyaluronidase added to the anaesthetic solution. Postoperative pain scores were not significantly different between the two groups but the post-injection pain score was greater (marginally significant) in the group with hyaluronidase added. CONCLUSION: The addition of hyaluronidase significantly improves the quality of the motor blockade achieved with sub-Tenon's local anaesthesia, but has no effect on the sensory blockade.

Adult↗
PubMed1994

Respiration of [14C]alanine by the ectomycorrhizal fungus Paxillus involutus.

The ectomycorrhizal fungus Paxillus involutus efficiently took up exogenously supplied [14C]alanine and rapidly converted it to pyruvate, citrate, succinate, fumarate and to CO2, thus providing direct evidence for the utilisation of alanine as a respiratory substrate. [14C]alanine was further actively metabolised to glutamate, glutamine and aspartate. Exposure to aminooxyacetate completely suppressed 14CO2 evolution and greatly reduced the flow of carbon from [14C]alanine to tricarboxylic acid cycle intermediates and amino acids, suggesting that alanine aminotransferase plays a pivotal role in alanine metabolism in Paxillus involutus.

Agaricales↗
PubMed1975

Primary spheroidal degeneration of the cornea in Labrador and northern Newfoundland.

The reported prevalence and severity of primary spheroidal degeneration in Labrador and nothern Newfoundland is based on a survey of 929 patients. The degeneration is associated with man in outdoor occupations and with pinguecula, but not with glaucoma. Ultraviolet radiation is a probable causative factor and prophylaxis using appropriately filtering glass a possibilty.

Adolescent↗
PubMed1969

Some effects on the blood vessels of the human forearm of local exposure to pressures below atmospheric.

1. Measurements were made of the initial rate of change of volume of the forearm when the limb was suddenly exposed to various pressures below atmospheric; this was taken to indicate the arterial inflow under these conditions.2. The relationship between arterial inflow and the change in external pressure was curvilinear, with the convexity towards the pressure axis. At -90 mm Hg inflow was increased more than fivefold.3. With short repeated exposures to negative pressure the inflow to the limb showed a progressive decrease for successive exposures until a steady value was obtained.4. The relationship between arterial inflow and the reduction of external pressure during short repeated periods of exposure (6th-10th exposures) was linear from ambient to -80 mm Hg.5. Measurements of forearm blood flow after one, four and ten exposures to reduced external pressure showed that vasoconstriction developed within 20 sec of the end of the exposure and took about 60 sec to disappear. There were only slight differences in the degree of vasoconstriction induced by the different numbers of exposures.

Adolescent↗