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R D Glock

Publications and source records attributed to R D Glock.

50 records · Page 3Linked to original sources
PubMed1977

Enteropathogenicity of various isolates of Treponema hyodysenteriae.

Isolates of Treponema hyodysenteriae from 25 geographically separated outbreaks of swine dysentery were tested for their ability to produce the disease. Clinical signs and lesions typical of acute swine dysentery were produced in 52 of 68 (75%) susceptible specific pathogen-free pigs that had been orally inoculated with pure cultures of 23 of 25 beta-hemolytic isolates. In addition, 13 weakly beta-hemolytic isolates of nondysentery origin with morphology similar to T. hyodysenteriae did not produce disease when orally inoculated into susceptible specific pathogen-free pigs. Two of these latter isolates, Puppy and B296, and one pathogenic, beta-hemolytic isolate failed to produce disease when orally inoculated into puppies.

Animals↗
PubMed1977

Effects of intramuscular injections of selenium and vitamin E on selenium-vitamin E deficiency in young pigs.

Effects of intramuscular injections of selenium and vitamin E on lesions in pigs with selenium-vitamin E deficiency syndrome were determined in 2 factorial experiments, using a total 69 pigs. The pigs were fed a selenium-vitamin E deficient, 22.3% protein ration, supplemented with methionine, minerals, and vitamins. Weekly intramuscular injections of isotonic saline solution, vitamin E, selenium, or vitamin E and selenium were given to the respective treatment groups. Selenium-vitamin E deficiency lesions occurred only in pigs that were given saline injections. Weekly intramuscular injections of either selenium (as selenous acid buffered to pH (7.3) at the rate of 0.05 mg/kg of body weight or vitamin E at the rate of 20 IU/kg of body weight or the combination of selenium and vitamin E prevented cardiac and skeletal myodegeneration, hepatic necrosis, and death. Significant increases of serum aspartate aminotransferase activity values were noted in pigs with liver, heart, or skeletal muscle lesions, but these increases were not correlated with the extent of the lesions. Vascular lesions, epicardial and endocardial hemorrhages, and yellow discoloration of body fat were not features of this experimentally induced disease. These lesions may be related to factors other than the deficiency of selenium, vitamin E, or selenium and vitamin E in rations previously used in reported studies.

Animals↗
PubMed1976

Actinomycotic peritonitis in a dog.

Actinomycotic peritonitis in a 5-year-old female German Shorthaired Pointer was characterized by abdominal enlargement, a draining tract in the paralumbar fossa, and chronic debilitation. Clinical recovery resulted from excision of a granulomatous abdominal mass in combination with initial penicillin therapy and prolonged (3 months) sulfonamide therapy.

Actinomycosis↗
PubMed1975

Survival of certain pathogenic organisms in swine lagoon effluent.

Six pigs from a closed herd with no evidence or history of salmonellosis or swine dysentery were fed effluent from an anaerobic lagoon on a farm where salmonellosis and swine dysentery were enzootic. Salmonella saint-paul was isolated from the effluent and fromthe feces and certain tissues of the pigs. Clinical signs typical of swine dysentery and enteric shedding of large numbers of spirochetes with the characteristics of Treponema hyodysenteriae were noted in 5 of the 6 pigs.

Animals↗
PubMed1974

Localization of spirochetes with the structural characteristics of Treponema hyodysenteriae in the lesions of swine dysentery.

The large intestines of pigs with swine dysentery were examined by phase, light, and electron microscopy at intervals up to 11 days after oral inoculation with mucosal scrapings from infected pigs. Large spirochetes with the structural characteristics of Treponema hyodysenteriae were found only in infected pigs and were first observed in small numbers in the lumen of the large intestine 2 days after inoculation. Numerous large spirochetes were present on the luminal surface and in mucosal crypts as lesions developed. Degenerative changes were first observed in the apical portion of epithelial cells in close contact with large spirochetes. These large spirochetes were found intact in goblet cells and epithelial cells in the early stages of the disease and were numerous within degenerating epithelial cells as lesions became more advanced. Invasion beyond the lamina propria was not detected. These observations demonstrated the relationship between pathogenic large spirochetes and the mucosa of the large intestine in a specific disease, swine dysentery.

Animals↗
PubMed1972

Swine dysentery.

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Animals↗