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R D Lawrence

Publications and source records attributed to R D Lawrence.

12 recordsLinked to original sources

Crash reconstruction and injury-mechanism analysis using event data recorder technology.

Sophisticated onboard crash-event data recorders (EDRs) that log key vehicle dynamics information can be used to improve crash reconstruction, model occupant response, study the mechanisms of injury, and estimate occupant injury probabilities in near-real time. Such an EDR was developed and utilized as part of the Automatic Collision Notification (ACN) system for the National Highway Traffic Safety Administration. This paper presents the results of a study in which the reconstruction of an actual crash was augmented using EDR/ACN-supplied three-dimensional acceleration and other data in a vehicle occupant model configured using the Articulated Total Body (ATB) computer code. ATB-generated occupant-motion imagery and body-region acceleration response information provided valuable insights that permitted crash-reconstruction specialists to ascertain the true nature of the collision and identify the probable cause of an injury suffered by one of the victims. The authors also posit that the use of EDR data from an ACN-type system as inputs to occupant crash-response modeling may be someday support crash-victim emergency medical treatment and triage.

Acceleration↗

Detection of Chlamydia pneumoniae in atherosclerotic plaques in the walls of arteries of lower extremities from patients undergoing bypass operation for arterial obstruction.

PURPOSE: To study surgically excised vascular tissue from lower extremities for the presence of Chlamydia pneumoniae, to extend the previously described association of the organism with atherosclerosis. METHODS: Arterial biopsy specimens obtained from femoral and popliteal arteries during bypass operation for claudication were examined by immunocytochemical analysis and polymerase chain reaction for the presence of organisms. RESULTS: C. pneumoniae was detected in atherosclerotic plaques by either method in either artery of 11 of 23 patients (48%). Eight of 21 popliteal and three of 18 femoral arteries had positive results. CONCLUSIONS: Detection of C. pneumoniae in peripheral arteries indicates that the organism is widespread in atherosclerosis of the vascular system.

Adult↗

Chlamydia pneumoniae (TWAR) in atherosclerosis of the carotid artery.

BACKGROUND: Chlamydia pneumoniae has been demonstrated in atherosclerotic lesions of coronary arteries and aorta. A seroepidemiological study found C pneumoniae-specific antibody more frequently in persons with significant carotid artery wall thickening than in matched control subjects. METHODS AND RESULTS: Fresh-frozen or formalin-fixed tissue obtained at carotid endarterectomy was examined by immunocytochemistry (ICC) and the polymerase chain reaction (PCR) for the presence of C pneumoniae. Five of five fresh-frozen and formalin-fixed carotid endarterectomy specimens were positive for C pneumoniae by ICC (three of five by PCR). A total of 56 archival formalin-fixed, paraffin-embedded carotid endarterectomy tissues from three hospitals were examined by ICC. Thirty-two were positive. Thirteen normal carotid artery tissue sections from six patients were negative for C pneumoniae. CONCLUSIONS: C pneumoniae organisms are frequently found in the advanced carotid atherosclerotic lesions of persons undergoing endarterectomy. Although these findings do not establish causality for C pneumoniae in carotid artery atherosclerosis, they should stimulate investigation of a possible causal or pathogenic role for the organism in the disease.

Aged↗

Inaccuracy of measuring wounds on autopsy photographs.

This paper demonstrates the inaccuracy of using a ruler placed in an autopsy photograph for measuring wounds shown in that photograph. Wounds should be measured, not on the photographs, but on the body, and dimensions should be recorded in the autopsy protocol.

Autopsy↗

Suicidal electrocution in a bathtub.

A case of suicidal electrocution in a filled bathtub is presented with a discussion of the mechanism of electrocution in water. A modern safety device, the Ground Fault Interruptor Circuit, is also described.

Electric Injuries↗