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R D Neff

Publications and source records attributed to R D Neff.

11 recordsLinked to original sources
PubMed1985

Measurement of absorbed dose from radionuclide solutions mixed intimately with the FBX dosimeter.

Chemical dosimeters are used widely for accurate measurement of large radiation doses due to external beam irradiation from radionuclide sources and from particle accelerators. Their use for measurement of absorbed doses from radioactive solutions mixed in the dosimeter solution was reported as early as 1952, but the large activities needed to produce suitable absorbance values in the relatively insensitive dosimeters of that time discouraged further work. This manuscript reports the results of an investigation into the suitability of the ferrous sulfate-benzoic acid-xylenol orange (FBX) dosimeter for measurement of small absorbed doses caused by radionuclide solutions mixed with the dosimeter solution. The FBX dosimeter exhibited a linear dose response as a function of activity for two common radiopharmaceuticals, 99mTc sodium pertechnetate and 131I sodium iodide. Conditions under which the FBX dosimeter may be used with radionuclide solutions were studied and were found to be amenable to routine use by laboratories possessing relatively unsophisticated instrumentation. That any radionuclide could be studied using this dosimeter appears likely.

Benzoates↗
PubMed1977

Control of radiation in animal facilities.

Use of radioactive materials in animals for research and clinical studies is on the increase. These studies may be undertaken with little or no disruption of normal facility operations if a few facts are considered. The primary factor of consideration is the radiopharmaceutical--its pharmacologic behavior and physical characteristics. The preferred radionuclide is one with the shortest half-life compatible with the variables to be measured. The fact that an animal is a source of radiation as well as a potential source of contamination must be kept in mind. Improper use of radiopharmaceuticals is inexcusable.

Animals↗
PubMed1975

Lymphocyte depletion in peripheral blood of acutely gamma-irradiated rats.

Groups of albino rats were exposed to 200, 800, 2000 and 5000 R of 60-Co gamma-radiation. Peripheral blood samples were taken from the tail at 1, 2, 4, 8 and 24 hours after irradiation. Calculation of the lymphocyte count per unit blood volume was made for each sample. Control rats were also mock-irradiated and sampled in the same manner. The time response of the lymphocyte count indicated that within the first hour, there was a drastic prompt drop. From one to eight hours after irradiation, the counts declined continuously, and from eight to twenty-four hours less rapidly. The depletion rates for the one to eight hour period were calculated and found to be statistically different for all groups, except between 2000 and 5000 R.

Animals↗