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R D O'Brien

Publications and source records attributed to R D O'Brien.

68 records · Page 4Linked to original sources

Psilocybin: reaction with a fraction of rat brain.

Psilocybin, a hallucinogen, formed a blue color with a subfraction of rat-brain mitochondria believed to contain nerve-ending particles. Color formation increased with pH, did not require oxygen, and involved a component that could not be solubilized. The effect was not shown by chemically related neuroactive compounds, such as bufotenine and serotonin, and was antagonized by only tyramine or ethylenediaminetetraacetic acid.

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