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Biomedical subjects

R D Snow

Publications and source records attributed to R D Snow.

10 recordsLinked to original sources

Dynamic magnetic resonance imaging in evaluating suspicious breast lesions: correlation with pathologic findings.

BACKGROUND: We used dynamic magnetic resonance imaging (MRI) to study breast lesions in 13 women. METHODS: We observed differences in contrast uptake between benignancy and malignancy in 14 suspicious breast lesions. Three-dimensional (3D) gradient echo sequences were obtained before and after administration of gadolinium-based contrast medium (0.16 mmol/kg). The percentage of signal increase in lesions was measured in a series of five 90-second sequences, and time-enhancement patterns were correlated with pathologic diagnoses. RESULTS: Seven benign lesions and three breast cancer recurrences showed less than 185% signal increase at 90 seconds after contrast administration. Three new breast cancers and one recently biopsied benign lesion showed more than 185% signal increase at 90 seconds. CONCLUSION: Using this MRI technique, we can discriminate between new breast cancers (more than 185% early signal increase) and breast cancer recurrence and/or benign lesions (less than 185% early signal increase) but cannot distinguish recurrent from benign lesions.

Breast↗

Neuroradiologic findings in Marinesco-Sjögren syndrome.

PURPOSE: Our purpose was to determine the neuroradiologic findings of Marinesco-Sjögren syndrome on plain skull radiographs, CT, and MR images. METHODS: Eight patients with proved Marinesco-Sjögren syndrome (age range, 4 to 56 years) had a total of nine CT scans, seven MR imaging studies, and two plain radiographic examinations of the skull. The findings were reviewed retrospectively, with particular attention to the size of the posterior fossa and cerebellum. RESULTS: All patients had hypoplastic cerebellar hemispheres and a hypoplastic vermis in a small posterior fossa. One patient had a midline posterior fossa cyst and another had agenesis of the corpus callosum. CONCLUSION: Hypoplasia of the cerebellar hemispheres and the vermis and a small posterior fossa are the most prominent neuroradiologic findings in Marinesco-Sjögren syndrome.

Adolescent↗

Skeletal findings in Marinesco-Sjögren syndrome.

OBJECTIVE: To describe the appearance and frequency of skeletal abnormalities associated with the Marinesco-Sjögren syndrome of cerebellar ataxia, congenital cataracts, mental and physical retardation and myopathy. SUBJECTS AND METHODS: Seventeen individuals affected with the disorder, of common ancestry and marked consanguinity, were found in an isolated area in southwest Alabama; 11 were available for radiologic examination of parts of the skeleton. The range and frequency of skeletal abnormalities thus demonstrated were tabulated. RESULTS AND CONCLUSION: A constellation of cranial and extracranial skeletal abnormalities-including a small posterior fossa, spinal abnormalities, gracile bones, elbow and hip valgus and asymmetric metacarpal and metatarsal shortening- can lead the radiologist or orthopaedist to suggest the diagnosis, especially if appropriate neurological/neuroradiological findings also are present.

Bone and Bones↗

Stenotic origin of an aberrant left subclavian artery from a right-sided aortic arch. A case report.

A patient with a right-sided aortic arch giving origin to an aberrant left subclavian artery with circumferential ostial stenosis is reported. This asymptomatic anomaly was discovered serendipitously during cerebral arteriography for subarachnoid hemorrhage. The embryologic origin of this anatomic variant is discussed, as are some practical implications relating to the angiographic technique of selective catheterization of branches of the aortic arch.

Adult↗

MR imaging of spinal nerve roots: techniques, enhancement patterns, and imaging findings.

The purpose of this report was to review the MR techniques, contrast enhancement patterns, and MR imaging findings for the spinal nerve roots. The phenomenon of contrast enhancement of the nerve roots and its relationship to disk disease and failed-back-surgery syndrome are discussed. The MR imaging findings for various inflammatory and neoplastic disorders affecting the spinal nerve roots are described and illustrated.

Contrast Media↗

Musculoskeletal findings in Klippel-Trenaunay syndrome.

Klippel-Trenaunay syndrome is an angio-osteohypertrophy syndrome without deep arteriovenous malformations. Clinical manifestations consist of vascular nevi, varices, and bony and soft-tissue hypertrophy. On skeletal imaging, there was extensive radionuclide uptake in a massively enlarged right lower extremity.

Bone and Bones↗

Enhancing transdural lumbar disk herniation.

Transdural migration of an intervertebral disk fragment is accompanied by more severe clinical manifestations than the more common extradural disk herniation. We report on two patients with transdural lumbar disk herniation who had had no previous surgery. In both, there was intense enhancement of the intradural disk material on magnetic resonance imaging. The pathological specimen showed vascularization of the intradural fibrocartilage in one patient.

Adult↗

Hypertrophic synovitis and osteoarthritis of the cervical facet joint. Report of two cases.

We report two cases of cervical facet joint osteoarthritis associated with radiculopathy. Contrast-enhanced computed tomography showed a halo of enhancing soft tissue surrounding the facet joints and narrowing the neural foramen. Hypertrophic synovial masses were discovered and removed at the time of operation in each case, resulting in relief of the radicular symptoms.

Aged↗