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Biomedical subjects

R D Stone

Publications and source records attributed to R D Stone.

36 records · Page 2Linked to original sources
PubMed1983

Choroidal melanoma growth patterns.

Thirty patients with choroidal melanoma in whom tumour thickness was found to increase on serial examination were retrospectively studied. Often when tumours started to increase in thickness, after a period of relative quiescence, the growth rate was relatively rapid. Increased tumour thickness was associated with increased tumour growth. During the phase of active tumour growth the height of the lesion tended to increase more than exponentially. Possible inadvertent biases in the selection of the patients studied prohibit wide-ranging conclusions from these data.

Choroid Neoplasms↗
PubMed1981

Monocular axial myopia associated with neonatal eyelid closure in human infants.

We studied eight infants who developed unilateral axial myopia associated with neonatal eyelid closure. Clinical findings and ultrasonographic biometric measurements suggested that axial elongation of the eye may occur as a result of neonatal eyelid closure, a finding similar to that for experimental myopia produced in neonatal animals after eyelid fusion. Early treatment of eyelid occlusion in the neonate may prevent axial myopia and subsequent anisometropic amblyopia.

Blepharoptosis↗
PubMed1981

Orbital melanoma.

A case of choroidal melanoma metastatic to the contralateral orbit is presented. Ultrasound and orbital computerized tomographic scan data are shown. In patients with a history of choroidal melanoma and a contralateral orbital mass, metastatic orbital melanoma should be suspected.

Aged↗
PubMed1980

Diagnostic modalities in choroidal melanoma.

We prospectively studied 51 patients with choroidal melanomas in a masked manner to determine the accuracy of clinical, ultrasound, and fluorescein diagnosis as well as the accuracy of tumor size measurements. In patients with clear media, clinical diagnosis was the most accurate means of detecting a choroidal melanoma. There was excellent correlation between clinical, ultrasound, and pathology measurements of tumor size. In small melanomas, clinical examination was the most accurate means of measuring tumor diameter and ultrasound the most accurate method of measuring tumor height. Even with a trained ocular oncologist, there was a significant variability in tumor measurements on serial ophthalmoscopic examinations.

Choroid Neoplasms↗
PubMed1980

Helium ion charged particle therapy for choroidal melanoma.

Nine patients with choroidal melanomas were treated with helium ion charged particle irradiation. No patient demonstrated tumor enlargement, and most lesions followed for more than five months have demonstrated tumor shrinkage. The most effective method of choroidal melanoma management is unclear. Heavy charged particle irradiation may be more applicable and have less ocular morbidity associated with it in either radioactive plaques or photocoagulation.

Adult↗
PubMed1980

Diffuse melanoma of the choroid.

An 81-year-old woman with good vision was followed up with the diagnosis of a minimally active melanoma. This tumour was eventually found to be a diffuse melanoma with extraocular extension. Diffuse melanomas of the uvea are difficult to diagnose, have frequent and early extrascleral extension, and have a poorer prognosis than most melanomas of the uveal tract.

Aged↗
PubMed1979

Pupillary membrane excision and anterior vitrectomy in eyes after uveitis.

Three patients with uveitis and dense pupillary membranes, total synechial closure of the angle, and low or normal pressure, underwent membranectomy and anterior vitrectomy via a limbal approach using scissors and a vitrectomy instrument. Postoperatively all regained useful vision that has been maintained for over two years despite the persistence of angle closure in all cases and severe hypotony in two.

Adult↗
PubMed1977

An ultrasonographic study of the persistence of buckle height three years after segmental sponge explants.

We studied a consecutive series of rhegmatogenous retinal detachments treated with segmental silicone sponge explants and cryotherapy, with or without drainage, approximately three years postoperatively by ultrasonography to determine the degree and persistence of the height of the buckle measuring 1.5 to 3 mm remained in all patienst examined clinically and ultrasonographically at three years or later. Five of these patients reexamined one year later demonstrated no loss of buckle height between the third and fourth postoperative years. By comparison, in a small group of patients examined early in their postoperative course (2.5 to 4 months), the buckles were only slightly higher than in the group studied at three years. Buckle height thus appeared to stabilize relatively quickly postoperatively and to persist at least three years. We believe encapsulation of the sponge by scar tissue must contribute to the long-term maintenance of buckle height.

Cryosurgery↗
PubMed1977

Vitrectomy.

Explore the source record for details and available documents.

Humans↗
PubMed1976

Glaucomatous cupping of the optic disk by ultrasonography.

B-scan ultrasonography was used to evaluate advance glaucomatous cupping of the optic disk (0.7 cup/disk ratio or greater) in one normal subject and six patients with glaucoma. The normal eye emitted a continuous echo from the posterior pole, which conformed to its mild degree of concavity. The glaucomatous eyes emitted echos from the posterior pole, demonstrating the more extreme concavity of the optic cup. Ultrasonographic evaluation of an acrylic plate containing holes of known diameter demonstrated the limits of resolution and artifacts that resulted from this examination.

Glaucoma↗