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R D Zecevic

Publications and source records attributed to R D Zecevic.

4 recordsLinked to original sources
PubMedDate not supplied

[Tuberous sclerosis].

Tuberous sclerosis is a rare hereditary disease which appears immediately after birth of during the second and third year of life. It is a multiorgan disorder characterized by convulsions, mental retardation and focal angiofibromyoma. The main findings are brain lesions including tuberous and astrocytes hamarthomas by which this disease was named. Renal alterations are angiofibromyolipoma and cysts, which are present in 40-80% of patients. The diagnosis is based on clinical, radiological and histological findings. This disease has a progressive course and fatal outcome. The therapy is symptomatic and surgical. The aim of this paper was to present this rare disease, which occurred in this patient during fourth year of life. Besides brain changes the patient also has extensive morphological renal alterations and renal failure. She died in 40th year of life due to multiorgan dysfunction.

Adult↗
PubMedDate not supplied

[Significance of deposits of immunoglobulins G, A, M and C3 complement component in the basal membrane zone of clinically unchanged skin for the diagnosis and evaluation of systemic lupus erythematosus activity].

Direct immunofluorescent test of clinically unaltered skin, the so-called lupus band test (LBT) was performed in 38 patients with systemic lupus erythematosus. Test was positive in 23 patients or 60.52%, respectively. It was established that the relative number of LBT positive patients was increased, from 37.5% in the group with the lowest disease activity determined by SLEDAI score, over 66.66% in the group with moderate activity till 100% in the patients with extremely active disease. Comparison of SLEDAI score (disease activity) mean values in the group of patients with systemic lupus erythematosus (SLE) with positive LBT compared to the group with negative LBT revealed statistically significant difference (< 0.05) in favour of the first group. No significant disease activity among patients' groups, formed according to the types and number of registered immunoreactants was observed. LBT in patients with SLE should be done in prognostic purposes. Positive LBT indicates the more active disease. Besides, the test can be a valuable diagnostic indicator in patients who do not fulfill the diagnostic criteria of American College of Rheumatology.

Adolescent↗
PubMedDate not supplied

[Treatment of eosinophilic fasciitis with cimetidine].

A case of a female patient with clinical and histological manifestation of eosinophilic fascitis has been reported. After five months cimetidine therapy a significant improvement was achieved. During the therapy some adverse effects occurred and cimetidine therapy had to be ceased.

Cimetidine↗