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Biomedical subjects

R D'Ascenzo

Publications and source records attributed to R D'Ascenzo.

11 recordsLinked to original sources
PubMed1998

[Colposuspension with propylene mesh. A new technique for correction of urinary stress incontinence].

The results of colposuspension for correcting urinary stress incontinence, both transabdominal, like Burch procedure, and transvaginal like Stamey-Pereyra procedure are, up to date, good, but not perfect at long-term. The cutting of the tissues from distal end of the sutures seems to be the main reason of failure of the operation. The authors propose a new technique of colposuspension by means of a particular suture made by the joining a prolene-mesh and a prolene-suture bilaterally placed along the urethra to obtain a strong, but natural support without risk of urethral erosion. The authors present the preliminary report of the first sixteen consecutive operations performed in patients with genuine urinary stress incontinence of first and second degree, according to Blaivas classification, diagnosed by medical history, objective findings, urodynamic tests and cystography. The follow-up in all the patients was six months: undoubtedly brief, but sufficient to refer on the feasibility and the efficacy of the procedure, the easy performing and the scarce onset of early complications as wound infection or troubles related to the prolene-mesh.

Adult↗
PubMed1992

[Seminal vesicles: echographic findings in 244 subjects. Evaluation of anatomic data and correlations with pathologic prostatic-vesicular parameters].

Over a 2-year period (1989-90), about 400 cases were examined (out of nearly 2,500 US examinations of the prostate), 244 of which had subsequent bioptic, surgical or autoptic confirmation. This paper reports the anatomic, clinical and pathologic data relative to the seminal vesicles of 244 subjects who underwent transrectal US of the prostate for different clinical indications. Our biometric values were slightly different from those reported in literature, the latter being based on autoptic findings. Agenesis and monolateral ectopia were confirmed to be extremely rare: 4 cases only (1.6%) in our series. A typical finding was the nearly perfect symmetry; in size and structure, of the two seminal vesicles in the same subject; as a matter of fact, a loco-regional pathologic condition was detected in all the patients (14) with asymmetry. A hundred per cent agreement was observed between the US patterns of the seminal vesicles and the prostatic patterns in case of acute/subacute prostatic inflammation involving also the 2 glands: this parameter can be used to follow the clinical course of the inflammatory process.

Adult↗
PubMed1992

Transperineal vesiculodeferentography under ultrasound control: first experiences.

Vesiculodeferentography (VDG) plays an important role in diagnosing male infertility and staging of prostatic cancer; the techniques of performing the examination are, today, well codified: 1) retrograde, by endoscopic cannulation of ejaculatory ducts; 2) anterograde, by cannulation of the deferent duct surgically prepared at the scrotum. In order to avoid the difficulties of the first method and the risks in the second (like stenosis and fibrosis of the deferent duct) we propose a new simple and safe method based on the direct transperineal puncture of the seminal vesicle under direct echographic control with a transrectal probe. We have studied 16 patients, mainly in order to stage prostatic cancer; the procedure was easy to perform, well tolerated and without consequences at seminal level. It required only 30 minutes, without anaesthesia and with a very low cost. The method permits a clear visualisation of anatomical structures and of possible pathologies with particular reference to vesicular invasion by a prostatic cancer.

Catheterization↗
PubMed1991

[Color Doppler in the diagnosis of malignant prostatic neoplasia. Preliminary results].

In the field ultrasonic diagnosis the application of color code to the duplex Doppler signal is without doubt the most up-to-date method. The common knowledge according to which all heteroplastic structures need a large quantity of O2 and provoke the formation of new vessels with the angiogenesis factor, with particularly rapid, and tumultuous fluxes due to the presence of shunt, is the basis for the use of color doppler in research on neoplasia in the initial phase. The authors submitted 11 patients considered at risk, to an echocolor Doppler study of the prostate, with a transrectal biplane probe of MHz. The exclusive application of ultrasonography grey scale, permitted the diagnosis of malignant neoplasia in 5 of these subjects. The following "color" exploration led to a cancer diagnosis in 10 patients. A bioptic check carried out through transperineal way color guided allowed the diagnosis of 8 'adenocarcinomas' and 1 undifferentiated CA.

Adenocarcinoma↗
PubMed1990

[Transrectal echography and simultaneous uroflowmetry in the study of male urination. Considerations on 254 consecutive cases].

The authors report on a series of 254 consecutive male patients who underwent transrectal US, sometimes combined with uroflowmetry, for the study of micturitonal phase. 170 patients were studied with both techniques. In 118 patients, there was complete agreement between the two methods about presence and degree of flow obstruction; partial disagreement was observed in 48 patients and complete disagreement in 4. On 44/52 patients with partial/complete disagreement diagnostic cystouretrography was performed. Our results demonstrate high agreement between the two techniques, except in case of micturition deficit with columnar hypertrophic bladder and in obstructive pathologic conditions of anterior urethra.

Adult↗
PubMed1989

[Calcifications of the prostate: a transrectal echographic study].

Prostatic lithiasis is a well know phenomenon. It has little clinical significance and is not easily shown by conventional radiography, which has poor sensitivity and specificity. The authors have studied 612 patients with both suprapubic and transrectal US in order to 1) assess US sensitivity and specificity and 2) report the frequency, spatial distribution, number and features of prostatic calcifications with special emphasis on differential diagnosis between prostatic neoplasms and chronic prostatitis. The authors have also studied the relationship between morphology and symptoms and the results agree with those reported in the scanty literature. The authors conclude that the parameters studied are directly related to age, except for a younger group with clear evidence of genital inflammation. The authors emphasize the impossibility to correlate morphology of prostatic calcifications with pathologic conditions: there are no specific symptoms clearly connected with calcification even though the inflammation is often associated with calcifications.

Calcinosis↗
PubMed1989

[Ultrasound-guided prostatic biopsy using biplanar transrectal probe. Our experience].

In the last three years we performed more than 200 echo-guided prostatic biopsies using different probes. Recently, thanks to the availability of a bi-planar transrectal probe we have developed a technique that resulted simple rapid well accepted by the patients and above all able to center small prostatic nodules. We have studied with this technique 96 patients performing 120 biopsies. For the biopsy we used a 19 G cutting-needle introduced under local anaesthesia parallel to the probe (linear array) when the needle is on the target we turn on the axial view and we check the position with respect to the center of the lesion, then, returning to the sagittal view we perform 1 to 3 biopsies for microhistological and cytological examination. With this method we have reached a better accuracy of diagnosis.

Biopsy↗