Disposable gas sampling line leaks.
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Blood Gas Analysis↗
Biomedical subjects
R Daley
Publications and source records attributed to R Daley.
Sarcoidosis after antiretroviral therapy in a patient with acquired immunodeficiency syndrome.
A 53-year-old man with acquired immunodeficiency syndrome (AIDS) developed clinical and radiological features compatible with sarcoidosis 14 months after starting highly active antiretroviral therapy (HAART). The CD4 lymphocyte count had increased from 5 cells/mm(3) to 235 cells/mm(3) with HAART. Transbronchial lung biopsy showed nonnecrotizing granulomas. All studies for an infectious etiology were negative. His condition improved after treatment with corticosteroids. To our knowledge, this is the fifth case report of sarcoidosis occurring after initiation of antiretroviral therapy for AIDS.
Acquired Immunodeficiency Syndrome↗
Free flap transplantation in mice.
A new model is presented that adapts the standard experimental groin free flap model to the mouse. The femoral vessels upon which the microvascular anastomoses are based are very small (0.2-0.4 mm diameter in the artery), making this a technically challenging exercise. A 100% patency was achieved for flap replantation in ICR (outbred) mice. Success rates for flap transplantation in Balb/C (syngeneic) mice rose from 20 to 75% with modification of the anastomoses from end-to-end to end-to-side procedures. This model offers new avenues of investigation when combined with recently developed transgenic mouse models.
Anastomosis, Surgical↗
Metacarpal fracture angulation decreases flexor mechanical efficiency in human hands.
The most common fracture of the hand occurs at the neck of the metacarpal. Despite clinical studies, controversy remains as to how much fracture angulation should be tolerated before more aggressive reduction is required. A controlled biomechanical model was used to simulate fifth metacarpal head fractures in fresh human cadaveric hands. Fracture angulation was varied from 0 to 90 degrees at 10-degree intervals. We measured tendon excursion, tendon load, and work required to flex the small finger from full extension to full flexion with 10-degree incremental increases in vertex-dorsal angulation. Repeated measures analysis of variance revealed a significant decay in the efficiency of the flexor system when fracture angulation exceeded 30 degrees. Tendon excursion, load, and work requirements were all increased, confirming the detrimental effect of excessive fracture angulation on hand mechanics and function.
Biomechanical Phenomena↗
A 3-year clinical trial to compare efficacy of dentifrices containing 1.14% and 0.76% sodium monofluorophosphate.
A 3-yr daily supervised toothbrushing study with a double blind design was conducted to evaluate the anticaries effectiveness of a 1.14% sodium monofluorophosphate (MFP) dentifrice (1500 ppm F) compared to a 0.76% MFP dentifrice (1000 ppm F). This study began with nearly 4000 children, primarily aged 8-11, in grades 3-5, residing in a nonfluoridated community in Florida. A total of 2415 children completed 3 yr of the study, representing 61% of the children who began the study. The results indicate a statistically significant (P less than 0.001) anticaries benefit was derived over a 3-yr period from the use of the higher fluoride dentifrice (1500 ppm F) when compared to the positive control (1000 ppm F). Percent reductions in mean dental caries increments were 20.9%, 22.1%, 21.8%, 24.3%, and 35.2% for DMFT, DFT, DMFS, DFS, and DFS Interproximal, respectively.
Adolescent↗
Early post-surgical prosthetic fitting with a pre-fabricated plastic limb.
Early prosthetic fitting and independent ambulation are major goals in the rehabilitation of amputees with early walking being extremely valuable in the physical and psychosocial rehabilitation of the amputee. With early resumption of weight bearing and ambulation, deterioration of postural reflexes can be prevented and the residual limb (stump) can be shaped for definitive prosthetic fitting. A new temporary prosthesis was evaluated in its use on new below-knee amputees. The prosthesis is a plastic, hollow form which fits over the conventional rigid, plaster postoperative dressing. It comes in one size and is cut to fit the patient. The prosthesis is readily available, needs little training for its application, can be re-used, and is inexpensive. Twenty-two consecutive patients treated at Hines Veteran's Administration Hospital and Loyola University Medical Center underwent below-knee amputations. All were determined to be potential walkers. The average age at surgery was 61 years with a range of 17 to 74 years. Amputation was performed for trauma in two patients and gangrene in the other 20. All wounds were dressed with conventional rigid, plaster dressings with cast changes five days postoperatively. The prefabricated temporary prosthesis was applied at the second cast application at an average of 8.1 days postoperatively with permanent prosthetic fitting at 7.7 weeks. There were no complications related to the use of the plastic temporary prosthesis. The use of a new plastic temporary prosthesis has been found to be advantageous in the early rehabilitation of below-knee amputees.
Adolescent↗
Massive dilatation of the left atrium.
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Cranial Nerve Diseases↗
Pulmonary oedema in pulmonary thromboembolism.
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Animals↗
Primary pulmonary hypertension: familial occurrence.
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Adult↗