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Biomedical subjects

R Djindjian

Publications and source records attributed to R Djindjian.

At least 19 recordsLinked to original sources
PubMed1978

[Development of therapeutic neuroradiology (author's transl)].

While therapeutic endovascular occlusions date from as early as 1904, it is in the last 20 years that therapeutic neutroradiology has come into its own. Progress has been made in four directions. (1) Embolization has developed from the original technique involving arteriotomy, through percutaneous methods, to present-day superselective catheterization. Concurrently, the materials used have been improved: from nonmalleable muscle and Silastic balls, to malleable Spongel and dura mater, and most recently to polymerizable fluid plastic substances. The possibility of obstructing very narrow vessels extends the range of indications of embolization. (2) Balloon catheters have been developed, first with nondetachable balloons (1971), more recently with detachable ones (1974). (3) Other techniques may be used to produce a therapeutic thrombosis, e.g., endovascular electrocoagulation and thermocoagulation. (4) Foreign bodies may be extracted safely by catheterization. Further development of techniques should ensure a growing importance for therapeutic neuroradiology in the future.

Embolization, Therapeutic↗
PubMed1978

Subarachnoid hemorrhage due to intraspinal tumors.

Five cases of subarachnoid hemorrhage arising from an intraspinal tumor are presented, Three of these were ependymomas in the region of the cauda equina. One was a neurofibroma at L1. The fifth was a hemangioblastoma in the upper lumbar region. The literature dealing with subarachnoid hemorrhage due to intraspinal lesions is reviewed. The majority of cases of spinal subarachnoid hemorrhage are due to arteriovenous malformations, but 50 cases in which the bleeding developed from a neoplasm have been reported.

Adolescent↗
PubMed1978

[Spinal meningeal hemorrhage due to tumors: a report on 5 cases with arteriography (author's transl)].

Meningeal hemorrhages in 5 patients with tumors of the cauda equina are reported. In each case there were signs from the brain area which led to a false diagnosis of ruptured intracranial aneurism, before attention was drawn to the cauda equina by a relapse with hemorrhage or other signs. The value of medullary arteriography for positively diagnosing cauda equina tumors, and their differential diagnosis from medullary arteriovenous malformations--principal cause of spinal meningeal hemorrhages--is discussed, as well as the necessity for systematically evoking this topography in children and young adults when arteriographic exploration is negative.

Adolescent↗
PubMed1977

Spinal cord arteriovenous malformations and the Klippel-Trenaunay-Weber syndrome.

Five cases in which the Klippel-Trenaunay-Weber syndrome was associated with a spinal cord arteriovenous malformation are reported: they formed part of a series of 150 spinal arteriovenous malformations. Hypertrophic lesions, dilated arteries and varicose veins were present in every case, but cutaneous angiomatosis was found in only two. In each case, there was an intramedullary AVM. The relationship of the Klippel-Trenaunay-Weber syndrome to the regional angiomatous phacomatoses is discussed.

Adolescent↗
PubMed1977

[Medullary angiomas and the Klippel-Trenaunay-Weber syndrome].

5 cases of an association of Klippel-Trenaunay-Weber syndrome and of spinal cord angiomas are reported amongst a series of 150 cases of malformation of the cord. The hypertrophic element, arterial dilatations and varices were found to be constant, in constant to cutaneous angiomatosis which was found in only 2 cases. There were intraspinal angiomas in all cases. The relationship between Klippel-Trenaunay-Weber syndrome and regional angiomatous phacomatoses are discussed.

Adolescent↗
PubMed1977

[Arteriography of intraspinal ependymomas].

Eleven cases of spinal ependymomas were studied by angiography. In four cases there was a tumoral blush, and in five cases, indirect signs of a spinal tumor. Although direct opacification of some caudal ependymomas is of great value, the main interest of spinal angiography is in the differential diagnosis with arterio-venous malformations, when there is a spinal S.A.H. or when there are abnormal vascular markings on the myelogram.

Adolescent↗
PubMed1977

[Anterior angiomas of the spinal cord and their treatment].

For a long time surgical removal of intra-medullary angiomas was considered as impossible. Accurate localization of the lesion by spinal angiography, microsurgical techniques allow to overcome this surgical challenge. 15 cases of spinal arteriovenous malformations fed by the anterior spinal artery have been operated. Criterias for surgery and post-operative results are mainly dependant upon the neurological states and the anatomical type of the malformations (type I, II, III, IV), Total removal of the malformations was performed in 12 cases with post-operative control angiography in seven instances.

Arteriovenous Malformations↗
PubMed1977

Intradural extramedullary spinal arterio-venous malformations fed by the anterior spinal artery.

There is a small group of spinal arteriovenous malformations which differ from all of the others. They receive their blood supply from the anterior spinal artery but are located outside of the spinal cord and its pia mater. Six such malformations from our series of 150 spinal arteriovenous malformations 1,4 are reported. They differ in their clinical manifestations from the others. They can be extirpated with improvement in the patient's clinical manifestations.

Adolescent↗
PubMed1976

[Super-selective cerebral angiography. III. Diagnostic use and therapeutic possibilities of the telescopic catheterization technic in the circulation area of the external carotid artery in man].

The diagnostic value and technical versatility of the previously described telescopic catheter system was demonstrated in 15 patients by super-selective angiography of the external carotid artery. It was possible in all patients to catheterise the individual branches with the F-catheter; the polyethylene-S-catheter could then be passed 3 to 5 cm, beyond the tip of the F-catheter. In almost half the patients, spasm of the injected artery was observed, particularly of the superficial temporal and external occipital arteries; this was reversed by intravenous papaverine and did not interfere with detailed diagnosis. It was usually possible to obtain filling of peripheral vessels, thereby demonstrating the territory of the middle meningeal artery, the scalp, sub-mandibular gland and the pinna. There were no complications as a result of the catheterisation. The usefulness and advantages of the telescopic catheter system for therapeutic neuro-radiological procedures, with embolisation of external branches in man, are discussed.

Adult↗
PubMed1976

Super-selective arteriography of branches of the external carotid artery.

Superselective arteriography of the branches of the external carotid artery is of great value in the diagnosis of vascular lesions in the distribution of this artery. These include vascular anomalies of the scalp, the tongue, the ears, the face, the dura mater, and intracranial sinuses, of meningiomas, glomus tumors, angiofibromas of the nasopharynx, and metastases. Super-selective catheterization of the branch of the external carotid artery can also be utilized for the treatment of these lesions by embolization. The technique is described and the various lesions illustrated.

Arteriovenous Malformations↗
PubMed1976

[Embolization by femoral catheterization of tumors supplied by the external carotid artery. 40 cases].

Experiences from therapeutic embolization by way of superselective catheterization of the external carotid artery, in 40 cases of cranio-cerebral, maxillo-facial and cervical tumours are reported. Using Spongel, embolization offered definite advantages compared to simple arterial ligation: it is easily performed as a supplementary procedure to diagnostic superselective angiography; a meticulous technique will provide superselective arterial occlusion with obstruction of vessels down to the precapillary size (diameter 150 to 200 mu). Embolization is advocated as a preoperative measure in meningeomas (particularly at the skull base), naso-pharyngeal angiofibromas, intracranial and cervical chemodectomas, in which cases profound bleeding during surgery may be expected and as a palliative measure in cases where surgery and radiation therapy fail to control recurrence of a tumour.

Carotid Artery, External↗