[Major cryptogenic polymorphic erythema of childhood].
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Biomedical subjects
Publications and source records attributed to R Douniau.
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Examination under an optical microscope of a radiolucent mandibular lesion showed a proliferation of histiocytes. Upon further examination of electron micrographs, the lesion showed the presence of Langerhans cell granules, within the histiocytes, thus confirming the clinical diagnosis of Hand-Schüller-Christian's disease. Microradiographic study of the canine tooth and the surrounding alveolar bone shows alveolar and root resorption, as well as signs of osteomalacia.
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The authors present a case of odontogenic tumour occuring at birth. Its origin seems to be an early modification of the ectomesenchyme. The course of the disease may be followed by lines within the dentin traced by courses of tetracycline during the first few years of life.
The lacrimals glands may be the focus of the pleomorphic tumours with the same property as the major and minor salivary glands. Their localisation causes different clinical and therapeutic consequences. The cylindromes or Adenoid Cystic Carcinoma are to be put on a parallel with the pleomorphic tumours, though the issue of the clinical evolution is very different for each of them.
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