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Biomedical subjects

R Dullerud

Publications and source records attributed to R Dullerud.

8 recordsLinked to original sources

[Intraoperative ultrasonography in brain surgery].

Intraoperative ultrasound was used in 33 patients. 19 lesions were primary malignant brain tumours, including 12 gliomas, three astrocytomas and four oligodendrogliomas. There were five metastases, three meningeomas, two dysembryoplastic neuroepithelial tumours and two angiomas. One patient had an arachnoid cyst, and another an infarct. The main advantage of carrying out intraoperative ultrasound examination is that it helps to localize the tumour, particularly in small subcortical lesions where the brain surface may appear normal. Ultrasound is less useful for characterizing the tumour, although the various tumours do show some differences. As a rule, the glioblastomas are inhomogeneous and poorly marginated, while low grade gliomas are more homogeneous and well marginated. Also meningeomas and metastases tend to be homogeneous and well marginated. Periofocal oedema is hyperechogenic compared with brain tissue, with an intensity between that of normal brain tissue and tumour mass. Cyst, calcification and haemorrhage are easily demonstrated.

Adenocarcinoma

[Stenosis of the internal carotid artery at the bifurcation. Radiologic definition and Doppler diagnosis].

One hundred internal carotid arteries with varying degrees of stenosis were studied by angiography and doppler ultrasound. We found the minimal diameter of a stenosis, measured in mm, more suitable as reference for the doppler-based method than verbal assessment of a stenosis as slight, moderate or pronounced. The sensitivity and specificity of maximal blood velocity to diagnose high-grade stenosis is satisfactory for screening patients who might benefit from endarterectomy. Spectral velocity spread, or comparison of the velocity in the stenosis with that of a cranial reference segment of the artery did not increase the sensitivity to detect low-grade stenoses.

Adult

Radiological assessment of stenosis of the internal carotid artery at the junction with the common.

Stenoses at the origin of 100 internal carotid arteries from patients with ischemic cerebrovascular disease were studied by intra-arterial angiography. Three principles were employed to evaluate the degree of stenosis: 1) verbal description, grading stenoses as mild, moderate of severe, 2) estimation of the true residual diameter, and 3) calculation of percent stenosis, defined here as the diameter of the artery at the origin relative to that at the level of the angle of the mandible. The true diameter, estimated to the nearest whole mm, corresponded well with the verbal description, and correlated significantly with percent stenosis. Since the true diameter is precisely defined, easy to estimate, and directly related to its hemodynamic effect, we suggest that this simple parameter, rather than the more commonly used, but more vaguely defined term "percent lumen reduction", is used to grade stenoses of the internal carotid artery.

Adult

Influence of CT on tumor classification of laryngeal carcinomas.

The routine use of CT in 51 consecutive patients with squamous cell carcinoma of the larynx revealed cartilage involvement or extralaryngeal tumor growth consistent with a T4 tumor which made 14 patients candidates for laryngectomy. Only 5 of these had a T4 classification by clinical examination while 8 cases were upstaged from T3. Except for one supraglottic tumor upstaged from T2 to T4, CT did not change the classification for T1 and T2 tumors, whose localization was mainly glottic, and there were 2 false-negative examinations. It is concluded that CT is mandatory only in advanced tumors of the glottic region or when the anterior commissure is involved. However, in suspected malignancies of the sub- or supraglottic regions CT should always be carried out because these patients are at an increased risk of unexpected deep tumor growth.

Adult

Coracoid process transfer for acromioclavicular dislocation.

Seventeen patients with complete separation of the acromioclavicular joint were operated on acutely with transposition of the coracoid tip to the clavicle. All the patients were examined after a mean follow-up time of 7.5 years. Twelve patients had good function, 3 had slight pain in extreme positions, and 2 had poor function with pain at rest. Eleven patients had the screw removed, 2 of them because of deep infection. In 3 patients the coracoid tip fragmented during the operation. Two patients had an unsatisfying cosmetic result. As long as nonoperative treatment gives equal or better long-term functional results, we do not recommend this operation in acute dislocations.

Acromioclavicular Joint

Adhesive arachnoiditis after lumbar radiculography with Dimer-X and Depo-Medrol.

Lumbar radiculographs were obtained in 252 patients with suspected disk herniation. Fifteen patients who underwent previous radiculography with Dimer-X plus Depo-Medrol exhibited adhesive arachnoiditis. This was not observed in 6 patients who received Dimer-X alone. No positive correlation between radiological diagnosis of adhesive arachnoiditis and clinical symptoms can be demonstrated. The authors suggest that steroids not be used intrathecally in combination with water-soluble contrast media.

Adult