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Biomedical subjects

R E Burge

Publications and source records attributed to R E Burge.

7 recordsLinked to original sources
PubMed1988

Towards a digital model for an electron-microscope image.

An image model is defined based on the boundaries between image regions with different textures and series of descriptions of those textures. Six models of texture are studied under the categories of pixel-based and region-based models. Several techniques for the determination of the unit-cell of textures are presented. The model is applied to the consideration of (a) image correction, (b) the classification of image texture, (c) image enhancement including averaging of detail in periodic specimens, and (d) image data compression. A floating point format, which provides a significant simplification for the Huffman code, is also introduced.

Algorithms↗
PubMed1987

X-ray microscopy and X-ray imaging.

Within a framework of an overview of the current status and potential of X-ray microscopy, a description is given of the development of the King's College scanning instrument which produced its first images in September, 1986. The instrument was mounted on the newly-built undulator beam line at the UK Science and Engineering Research Council's SRS synchrotron. There are consequently three sites worldwide where high-resolution X-ray microscopes with zone-plate optics are in operation. The other sites are BESSY-Berlin and NSLS-Brookhaven.

Animals↗
PubMed1979

An X-ray study of the cytoplasmic membranes of two gram-positive bacteria.

X-ray diffraction diagrams of partially disordered one-dimensional lattices of isolated bacterial cytoplasmic membranes are described and they provide a basis for suggesting possible molecular structures of bacterial membranes. Biochemical and electron microscope evidence points towards a lipid bilayer with a high degree of fluidity. The protein molecules are in a disordered configuration in the membrane.

Bacillus↗
PubMed1977

Optical and digital image processing in high-resolution electron microscopy.

A comparison is made of the deblurring by digital and optical processing of a single conventional bright field electron image of ferritin particles distributed on a carbon supporting film. The deblurring functions include the effects of the partial temporal and partial spatial coherence of the electron beam, the phase contrast transfer function of the objective lens and Weiner signal to noise optimisation. Practical aspects of the similar results achieved by the two methods are discussed. The relative advantages and disadvantages of the batch and interactive computer modes for picture processing are considered in an Appendix.

Computers↗