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Biomedical subjects

R E Carney

Publications and source records attributed to R E Carney.

13 recordsLinked to original sources

Effect of osteopathic medical management on neurologic development in children.

For 3 years, children between 18 months and 12 years of age with and without recognized neurologic deficits were studied at the Osteopathic Center for Children. Their response to 6 to 12 osteopathic manipulative treatments directed to all areas of impaired inherent physiologic motion was estimated from changes in three sensory and three motor areas of performance. Houle's Profile of Development was used to compare neurologic with chronologic age and rate of development, and scores were age-adjusted. Results in children after treatment were compared with those following a waiting period without treatment. Neurologic performance significantly improved after treatment in children with diagnosed neurologic problems and to a lesser degree in children with medical or structural diagnoses. The advances in neurologic development continued over a several months' interval. The results support the use of osteopathic manipulative treatment as part of pediatric healthcare based on osteopathic medical philosophy and principles.

Child↗

Referral preferences among the mental health professions.

A questionnaire presenting two clinical cases with questions about a diagnosis, type of treatment, and whether the respondent would treat or refer the person was administered to pastoral counselors, psychologists, social workers, and psychiatrists. Psychiatrists tend to see the most and social workers the least pathology in the cases. Psychiatrists see the least need for a psychometric evaluation, but no difference was found concerning need for a neurological examination. The majority prefer to treat the "neurotic" case, whereas there was an almost equal tendency to refer the "phychotic" case. Social workers most prefer to treat and pastoral counselors to refer the "psychotic" case. Overall, social workers refer the most, pastoral counselors the least. Credibility as referral source is ranked as follows: psychiatry, psychology, social work, counselors (both pastoral and marriage, family and child), with laymen ranking lowest. Rankings of credibility and effectiveness as referral sources are highly correlated. Furthermore, the more effective and credible a professional group, the supply of such persons is seen as ample.

Counseling↗

Modification of seldomycin factor 5 at C-3'.

Attempted removal of the 3'-hydroxyl group of seldomycin factor 5 via displacement of a sulfonate ester has led to 3'-epi-seldomycin factor 5. Removal of the hydroxyl group has been effected by the Barton procedure. The antibacterial activity of 3'-epi- and 3'-deoxyseldomycin factor 5 against various aminoglycoside-resistant strains is discussed.

Anti-Bacterial Agents↗

Spectinomycin modification. III Chloro-deoxy analogs.

9-Epichloro-9-deoxy-4(R)-dihydrospectinomycin (3), 9-chloro-9-deoxy-4(R)-dihydrospectinomycin (7), 9-deoxy-8, 9-epimino-4(R)-dihydrospectinomycin (6), and 9-epichloro-9-deoxy-spectinomycin (10) have been prepared and their structures established by proton magnetic resonance. These analogs are devoid of antibiotic activity.

Bacteria↗

Spectinomycin modification. II. 7-EPI-sectinomycin.

7-Epi-spectinomycin (9) and 7-epi-4(R)-dihydrospectinomycin (10) have been prepared and their structure firmly established by proton magnetic resonance. Both of these spectinomycin analogs are devoid of antibiotic activity.

Chemical Phenomena↗