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Biomedical subjects

R E Duncan

Publications and source records attributed to R E Duncan.

10 recordsLinked to original sources
PubMed1977

Natural history and treatment of renal vein thrombosis in children.

The general features and problems of renal vein thrombosis in children are first discussed. The records of 11 children with this condition, 7 ill neonates and 4 older children with burns, are then reviewed, indicating the clinical course of the disease, how they were treated, the results, and pathological findings. From this study, the natural history is assembled and a protocol for treatment is proposed. Supportive therapy is necessary in all cases to correct dehydration and sepsis. Many children will develop a consumptive coagulopathy. Others will develop pulmonary emboli associated with thrombosis of the inferior vena cava. Anticoagulation should be achieved for these two conditions. Nonvisualization of affected renal units upon initial urographic examination virtually assures an atrophic, functionless kidney later. Nephrectomy will be required because of hypertension, persistent infection, and scarring. Thrombectomy may be attempted when bilateral nonvisualization on urography is associated with a positive venacavogram.

Anticoagulants↗
PubMed1977

Radiation-induced bladder tumors.

A recent 25-year experience with patients treated for carcinoma of the uterine cervix who subsequently had bladder tumors is presented. Of the 3,091 patients treated 2,674 had received radiotherapy and 8 suffered vesical malignancies of varied histopathological type 6 months to 20 years after irradiation. This incidence rate is 299.9 per 100,000, which is 57.6 times that of the general female population. Benign radiation reactions of the bladder and the possible etiology of radiation-induced bladder cancers are discussed.

Adult↗
PubMed1977

Diagnosis of primary retroperitoneal tumors.

An analysis of 27 cases of primary retroperitoneal tumors and a review of the literature are presented. Techniques available for the diagnosis of these neoplasms are discussed. Sarcoma is the most common histopathologic type. A painful abdominal mass is the characteristic presentation. Echography, angiography and carbon dioxide pneumography may provide specific diagnostic information but further histopathologic correlation is needed. Angiography should guide the surgical approach routinely. Surgical excision is the treatment of choice for all tumors except for the lymphomas, which are radiosensitive. Radiotherapy has liberal application in the treatment of other histopathologic types.

Adult↗
PubMed1975

Squamous cell carcinoma of the ureterovesical junction after renal transplantation.

A case of squamous cell carcinoma of the bladder occurring at the ureterovesical junction in a renal transplant recipient is presented. References are made to ureteral obstruction in transplanted kidneys, the broader field of squamous cell carcinoma of the bladder in non-transplanted patients and the relationship of malignancy to transplantation. We anticipate that an ever increasing number of these unusual cases will be forthcoming in the urological literature as renal transplantation develops.

Carcinoma, Squamous Cell↗