Biomedical subjects
Publications and source records attributed to R E Dunley.
An example of palatal necrotizing sialometaplasia is presented, and the clinical and microscopic features suggestive of squamous-cell carcinoma and mucoepidermal carcinoma are noted. The patient's health status, as shown by a rather thorough work-up, was unremarkable during the period which would seem to preclude a systemic etiology of this disease. The resolution of the lesion with minimal therapy is documented.
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A preparation commonly used as a local anesthetic in dentistry has been studied for the presence of antimicrobial activity. The solution, 2% Xylocaine®, with 1:100,000 epinephrine, was shown to inhibit the growth of certain organisms and to be cidal to others. Its cidal activity was significantly less than that of 2% Xylocaine without epinephrine (p < .05). Both solutions demonstrated statistically significant cidal activity when compared to controls (p < .005).