Simulation of clinical scintigrams for nuclear medicine imaging devices.
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Biomedical subjects
Publications and source records attributed to R E Dye.
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A novel fabrication technique is described based on stacking accurately drilled lead discs to form collimators for rectilinear scanning. This technique has proved successful for the construction of collimators across a wide range of imaging performance.
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A 36-year-old man had chronic, debilitating diarrhea due to cryptosporidiosis. This patient had longstanding common variable hypogammaglobulinemia and recurrent bacterial infections. Immunologic evaluation after discovery of Cryptosporidium showed lymphopenia with persistently reduced numbers of helper/inducer cells (OKT-4), variable numbers of suppressor/cytotoxic cells (OKT-8), OKT-4/OKT-8 ratio of 0.09, and increased levels of serum alpha-interferon, all of which describe the acquired immunodeficiency syndrome. Oocysts of Cryptosporidium were found in feces from the patient's cat, thus identifying a possible source of his infection. The patient had disseminated candidiasis, cytomegalovirus pneumonia, and cryptosporidiosis when he died.