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Biomedical subjects

R E Eilert

Publications and source records attributed to R E Eilert.

At least 19 recordsLinked to original sources
PubMed2001

Congenital dislocation of the patella.

Congenital dislocation of the patella may occur as a persistent lateral dislocation of the patella that presents with a knee flexion contracture and the patella tethered lateral to the femoral condyles or as an intermittent dislocation of the patella. In the latter syndrome, the patella dislocates completely with each flexion and extension cycle of the knee and is best termed obligatory dislocation of the patella, because the patient has no control over the patella dislocating as he or she moves the knee. The first type of congenital dislocation, which is fixed, often is associated with syndromes such as arthrogryposis and should be corrected surgically by lateral release and realignment of the patella. Obligatory dislocation of the patella tends to be an isolated dysplastic anomaly and may be relatively well tolerated. Rebalancing of the patella usually is done at a later age because of less interference with function. The current author describes the natural history of patella femoral dysplasia, detailing the pathologic changes that are present, and recommends surgical techniques for correcting both types of congenital dislocation of the patella.

Child↗
PubMed2000

Fibular hemimelia: comparison of outcome measurments after amputation and lengthening.

BACKGROUND: Treatment of fibular hemimelia includes either Syme or Boyd amputation with early prosthetic fitting or tibial lengthening. Numerous studies have documented the success of both procedures. The purpose of our study was to compare the outcome after amputation with that after tibial lengthening, specifically with regard to activity restrictions, pain, satisfaction, complications, number of procedures, and cost, in children with fibular hemimelia. METHODS: Thirty limbs in twenty-five patients treated with either an amputation or a lengthening procedure and followed for at least two years were studied. Fifteen patients underwent amputation, and ten patients underwent lengthening of the tibia. The mean age was 1.2 years at the time of amputation and 9.7 years at the time of initial lengthening. The mean duration of follow-up was 6.9 years after the amputations and 7.1 years after the lengthening procedures. RESULTS: The patients who underwent amputation were able to perform more activities than those who had a lengthening (mean activity score, 0 compared with 1.2 points; p<0.05), and they had less pain (mean pain score, 0.2 compared with 1.2 points; p = 0.091), were more satisfied and had a lower complication rate (0.37 compared with 1.91; p<0.05). The patients who underwent amputation also had fewer procedures (1.9 compared with 7.0; p<0.05), at a lower cost ($7016 compared with $26,900; p<0.05), than those who had a lengthening. Lengthening was successful in equalizing limb lengths; the mean limb-length discrepancy, assessed in nine of eleven limbs, was 0.7 centimeter. CONCLUSIONS: This study demonstrated that children who undergo early amputation are more active, have less pain, are more satisfied, have fewer complications, undergo fewer procedures, and incur less cost than those who undergo lengthening. This was true even though good results were obtained with the lengthening procedures and most patients achieved limb-length equality, were able to walk, had minimal pain, and were quite active.

Adolescent↗
PubMed1999

Children's and parents' visual perception of physicians.

The purpose of this study is to evaluate the child's and parents' visual perception of physicians. To do this, 50 children and their parents were asked which physician they preferred, when shown eight pairs of photographs. Four characteristics were tested twice, white coat versus no white coat, smile versus stern face, cartoon posters versus no posters, and standing versus stooping. We found that both children and parents preferred the smiling physician and the physician with cartoon posters on the wall. Surprisingly 54% of children preferred the physician in the white coat, whereas only 35% of parents preferred the white coat. Sixty-eight percent of children also preferred the standing physician compared with only 41% of parents. There was little correlation between the parent's and child's answers. The results did not differ significantly with age, gender, or number of hospitalizations. In conclusion our study did not confirm the popular belief that children are afraid of physicians in white coats, although children did strongly prefer physicians who smiled and those with cartoon posters on the wall.

Adult↗
PubMed1996

Results of the Wagner and Ilizarov methods of limb-lengthening.

We compared the results of the Wagner method of limb-lengthening in twenty extremities (nineteen patients) with those of the Ilizarov method in twenty-one extremities (eighteen patients). The Wagner external fixator was used in all twenty procedures in which the Wagner lengthening method was performed and in fourteen procedures in which the Ilizarov lengthening method was performed. The Ilizarov external fixator was used in the remaining seven procedures in which the Ilizarov method was performed. The average increase in length was 5.4 centimeters (range, 2.8 to 8.0 centimeters) with the Wagner technique and 5.9 centimeters (range, 1.0 to 16.8 centimeters) with the Ilizarov technique. The rate for the lengthening phase was nine days for one centimeter of length with the Wagner technique and twelve days for one centimeter with the Ilizarov technique. The rate for the consolidation phase was forty-four days for one centimeter with the Wagner technique and twenty-six days for one centimeter with the Ilizarov technique. The group of patients who were managed with the Wagner technique had thirty major complications, and the group of patients who were managed with the Ilizarov technique had only thirteen major complications. Forth complications were associated with the use of the uniaxial Wagner external apparatus and sixteen, with the use of the multiaxial Ilizarov external fixator.

Adolescent↗
PubMed1996

Evaluation of the biomechanics of the hip following a triple osteotomy of the innominate bone.

The biomechanics of the hip joint were evaluated in seventeen patients (twenty-two hips), twelve to forty-one years old (mean, twenty-four years old), who had a triple osteotomy of the innominate bone for treatment of symptomatic dysplasia of the hip. The duration of follow-up ranged from 2.2 to 13.8 years (mean, 6.8 years). Hip load, the area of the weight-bearing surface, and stress were determined from measurements on pelvic radiographs that were made preoperatively, postoperatively, and at the time of the latest follow-up; the values were compared with those in twenty-one hips from control subjects. The Harris hip-rating system was used for clinical assessment. According to the biomechanical analysis, there was significantly less relative stress on the hip after the triple osteotomy and at the time of the latest follow-up (p < 0.001 for both) than there had been preoperatively. The decrease in stress was a direct result of a significant increase in the area of the weight-bearing surface of the hip (p < 0.001). The load on the hip was not altered significantly, with the numbers available. The functional outcome was improved substantially when the biomechanical goals were achieved. Through the application of basic biomechanical principles, we were able to demonstrate the biomechanical efficacy of a triple osteotomy of the innominate bone. We recommend the use of biomechanical analysis as an adjunct to the clinical decision-making process in the treatment of a dysplastic hip.

Adolescent↗
PubMed1993

Effects of inhibitory casts and orthoses on bony alignment of foot and ankle during weight-bearing in children with spasticity.

One theory about the improvements in gait seen in children with CP who use inhibitory casts holds that they are a result of better posture of the foot. To examine this theory, the authors used x-rays to document the position of the foot both before and during inhibitory casting to see whether there were measurable changes in foot posture that could be ascribed to the casts. The bony alignment of the ankle and foot was compared during weight-bearing with the children in and out of inhibitory casts (N = 12), static ankle-foot orthoses (N = 7) and articulated ankle-foot orthoses (N = 8). The only angle change which was significant was calcaneal inclination in the articulated AFOs versus out of the orthoses. There was no significant difference in any of the other angles in any of the groups.

Adolescent↗
PubMed1993

Disruption of the anterior cruciate ligament in a 4-year-old child.

Anterior cruciate ligament (ACL) injuries in children are rare. Thus, the natural history of ACL injuries in skeletally immature patients is unknown. This case represents the longest follow-up (11 years) reported in the literature of an ACL injury in a child of less than 5 years old.

Anterior Cruciate Ligament Injuries↗
PubMed1992

Hip flexion contracture in cerebral palsy. The association between clinical and radiologic measurement methods.

Hip flexion contracture was examined in 51 spastic cerebral palsy patients by three clinical methods and two radiologic methods. An extremely low association was found between the clinical and radiologic methods with no particular method, clinical or radiologic, showing a higher association. The method of clinical examination should be chosen by convenience. Radiologic measurements by the methods used did not add useful information.

Adolescent↗
PubMed1992

Autologous transfusions for orthopaedic procedures at a children's hospital.

We conducted a critical review of the use of autologous transfusions in orthopaedics at a tertiary-care children's hospital. The cases of 198 children who deposited blood before an orthopaedic operation were analyzed. There were 175 children who were enrolled in the program of preoperative deposit of autologous blood who later needed transfusion of blood; 73 per cent of them received only autologous blood. Seventy patients also had intraoperative salvage. We were unable to document a proved benefit of intraoperative salvage of blood in this group of patients. Forty patients had some difficulty donating autologous blood preoperatively, but these problems were rarely serious. Major human errors occurred in thirteen patients and resulted in some patients receiving homologous transfusions while autologous blood components were still available. Fifty-five (40 per cent) of all of the transfusions were administered in clinical circumstances that failed to meet generally accepted criteria for transfusion, and fifty-four (38 per cent) of the postoperative transfusions also failed to meet these criteria. This was true of the homologous transfusions in the study as well. Although an autologous blood transfusion is a generally safe procedure, it is not without risk, and human errors can occur. In light of the potential complications, surgeons should adhere to the standard indications for transfusion when administering autologous blood.

Adolescent↗
PubMed1991

Fracture through the stalk of pedunculated osteochondromas. A report of three cases.

Although fracture through the base of an osteochondroma is a well-recognized clinical entity, the fate of such fractures has never been documented. Recommendations concerning the treatment of these fractures are contradictory. Of the three cases of fracture through the base of a pedunculated osteochondroma observed in the last 12 years, two healed without problem, one in a patient with a solitary osteochondroma, the other in a patient with multiple osteochondromas. The third patient remained symptomatic one year after injury, and histologic evaluation of the specimen after surgical excision confirmed the diagnosis of fibrous nonunion of the fracture. Experience with fractures through the base of a pedunculated osteochondroma suggests that the majority of these fractures will heal without complication, regardless of whether they involve solitary or multiple osteochondromas. However, symptomatic fibrous nonunion of such a fracture may occur particularly when an osteochondroma is located near large, mobile tendons.

Bone Neoplasms↗
PubMed1991

Autograft versus allograft for benign lesions in children.

Benign bone lesions in children are often so large in size that there is not an adequate amount of bone available for an autograft to fill the resultant cavity after surgical curettage. This study compared autografts and allografts with respect to the time required and the success of graft incorporation. Fifty-four patients with 61 lesions were studied. Lesions were classified as small volume (less than 60 cc) or large volume (more than 60 cc) and were separated into four groups: small-volume autograft, large-volume autograft, small-volume allograft, and large-volume allograft. Allografts appeared comparable to autografts when small-volume lesions were treated. The healing time was slightly longer for allografts with an average period of 21 months versus 27 months for autografts. Autografts were superior to allografts in rate and completeness of healing for solitary large lesions. This increased efficacy presumes a somewhat older child in which an adequate amount of bone is available for an autograft. A young child with multicentric or polyostotic lesions can still achieve successful incorporation with allografts. In this study, 38% healed completely and 29% healed partially. Allografts have a distinct place in the treatment of benign bone lesions in children.

Adolescent↗
PubMed1990

Orthopaedic aspects of fragile-X syndrome.

Fragile-X syndrome is one of the most common inherited forms of mental retardation. An associated connective-tissue disorder involving elastin accounts for the most frequent musculoskeletal manifestations, which include severe flexible flat feet, excessive laxity of the joints, and scoliosis. At our institution, seventy-five (50 per cent) of the 150 male patients who had fragile-X syndrome had flat feet, eighty-five (57 per cent) had excessive laxity of the joints, and ten had scoliosis. Twenty-nine of the patients who had flat feet had been evaluated or treated, or both, by an orthopaedic surgeon before the diagnosis of fragile-X syndrome had been made. Only one of these patients had been referred for developmental and genetic evaluation, which suggests that the orthopaedic community is not familiar with this syndrome. The orthopaedist should consider the diagnosis of fragile-X syndrome in the evaluation of a mentally retarded boy or man who has a family history of mental retardation. The presence of flat feet and excessive laxity of the joints, associated with the characteristic facies, macro-orchidism, and behavior, justifies a referral for developmental and genetic evaluation. Early diagnosis is important for several reasons, including genetic counseling for the family, more efficacious medical treatment, and specialized education.

Adolescent↗
PubMed1982

Protonmotive force in muscle mitochondria.

The protonmotive force (delta p) of muscle mitochondria was measured by estimating the distribution of 14C-labeled TPMP (trimethylphenylphosphonium iodide) and 14C-labeled acetate across the inner membrane of muscle mitochondria. The matrix volume was simultaneously determined using 3H-labeled H2O and 3H-labeled mannitol and repeated drying to distinguish the label in these 2 compounds. Rapid separation of mitochondria from the incubation medium by centrifugation through silicone oil avoids the problems of potential anaerobic conditions associated with conventional centrifugation and large volumes of trapped media associated with filtration. The value for delta p (mean +/- SD) was 192+/- 26 mV in 30 determinations with rat muscle mitochondria during state 4. Measurement of oxygen consumption allowed calculation of membrane conductance (Cm,H+) which was 0.49 +/- 0.18 nmol of H+/min/mg protein/mV. The values for delta p and Cm,H+ are reported for a variety of experimental conditions and are consistent with Mitchell's chemiosmotic theory. Biopsy specimens obtained from human muscle gave state-4 delta p values of 197+/- 30 mV (n =5) and Cm,H+ values of 0.52 +/- 0.12 nmol of H+/min/mg/mV (n = 4). This delta p assay is the first described for coupled mammalian muscle mitochondria and will be useful in assessing membrane function.

Animals↗
PubMed1977

Varus derotational osteotomy of the femur in cerebral palsy.

Varus derotational osteotomy of the femur is designed to correct coxa valga and femoral anteversion which contribute to progressive hip subluxation and dislocation in certain cases of cerebral palsy. By the application of a careful preoperative evaluation, vigorous postoperative rehabilitation and treatment of complications, satisfactory results were obtained in 17 of 20 patients followed for one to 17 years after osteotomy. No hip subsequently dislocated and dysplastic acetabulae were predictably remodeled in those patients less than 8 years of age.

Cerebral Palsy↗
PubMed1976

Boyd and Syme ankle amputations in children.

The Syme and Boyd amputations at the ankle were compared in thirty-four children followed for three to sixteen years. Good results were found with both techniques. The best results occurred when the heel pad was aligned in the plantigrade position, which produced almost normal function of the heel pad. The Boyd technique was a surer method of obtaining such alignment but was technically more difficult. Both the Boyd and Syme techniques are recommended for ankle amputation in children, but a distinct advantage of one technique over the other could not be defined.

Adolescent↗