Friedrich's disease. Aseptic necrosis of the sternal end of the clavicle.
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Biomedical subjects
Publications and source records attributed to R E Fischel.
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A patient is reported with a severe type 2 Klippel-Feil syndrome, and absent ulna and ulnar ray. The severity of the musculo-skeletal involvement did not allow for corrective procedures. This uncommon association of skeletal malformations has not been previously reported. Since this syndrome has been described in families as a possible autosomal recessive trait, a 25% recurrence risk and the possibility of prenatal detection by fetal visualization methods should be taken into consideration.
Studies derived from analyses of radiographs and dissections of cadaveric wrists have been directed at testing and disproving the commonly held theories that link chip fractures of the os triquetrum with avulsion. The authors found that the mechanism of such injuries involved a chisel action of the ulnar styloid upon the dorsum of the os triquetrum; furthermore, the impact of a fall on the outstretched arm with the hand rigidly held in strong dorsiflexion and ulnar deviation could be forceful enough to fracture the body of the os triquetrum as well. In all cases a striking prolongation of the ulnar styloid, beyond the surface of the ulnar head, was consistently noted.
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Five cases of multifocal carcinoma of the large intestine are described, including one multifocal recurrence, the only one described in the literature. All of them were recognised radiologically before operation. The importance of a thorough examination of the whole colon in suspected cases is stressed, even when a single lesion has been demonstrated.
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Two hundred and eighty male patients were examined for either peptic ulcer or impotence. Thirty-six of these suffered from impotence in association with duodenal or stomach ulcer. Surprisingly, all thirty-six patients, having been afflicted with both conditions, complained about only one of them, those with ulcers not having been disturbed by their impotence and vice versa.