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Biomedical subjects

R E GARDNER

Publications and source records attributed to R E GARDNER.

At least 19 recordsLinked to original sources

Cardiac resuscitation through the intact chest.

External cardiac compression and external defibrillation were successful in resuscitating 27 consecutive dogs after the production of ventricular fibrillation. Twelve patients survived following circulatory arrest treated with closed chest cardiac compression and, when indicated, defibrillation. Five additional patients were successfully resuscitated but died in the hospital. In fifteen cases, resuscitation was not successful.

Animals↗

Postoperative parenteral nutrition.

Parenteral feeding is not an adequate substitute for oral feeding. Water and electrolytes can readily be supplied parenterally, but not all necessary nutrients. To provide the 2,000 to 2,500 calories per day needed for adequate energy and to avoid oxidation of protein, concentrations of dextrose as great as 25 per cent with an additional 5 per cent of ethyl alcohol have been used parenterally with success. Fat emulsions have been given intravenously with some success, but undesirable reactions in as many as 16 per cent of patients have been reported. Protein may be given as amino acids in solution with 10 to 15 per cent dextrose. Water-soluble vitamins may be lost through diuresis if administered intravenously; of these vitamin C is necessary to healing of wounds and appears to have special value in reactions to stress. If fat nutrition is impaired, deficiency in fat-soluble vitamins is to be expected; of these, vitamin K is important to production of prothrombin and therefore especially necessary to recovery from operation or injury.

Amino Acids↗

Peripheral arteriosclerosis; present concepts of management.

Three hundred patients with clinical manifestations of ischemia due to peripheral arteriosclerosis were studied. An accurate demonstration of the extent of the arterial occlusive process by means of aortography was of major importance in determining therapy and prognosis. The results from thromboendarterectomy to restore the arterial lumen in cases of segmental thrombosis or stenosis greatly exceeded those obtained from other methods of therapy for peripheral arteriosclerosis. The indications for and the limitations of lumbar sympathectomy as a palliative procedure are described. Medical treatment, except for the use of specific protective measures, was of little value in altering either the symptoms or prognosis.

Arterial Occlusive Diseases↗