Biomedical subjects

R E Googe

Publications and source records attributed to R E Googe.

3 recordsLinked to original sources

PubMed1985

Multisection-multiecho MR imaging: effect on image quality.

An analysis of the effects of multisection-multiecho imaging on signal intensity is presented using a gaussian excitation pulse. The number of sections acquired, size of the intersection gap, and the number of echoes were all varied independently to evaluate their effect on image intensity. The results indicate that one should take a conservative approach in multisection-multiecho imaging, leaving at least a 2-mm-intersection gap and approximately a 20-msec delay between section excitations to avoid image signal loss owing to partial saturation effects.

Magnetic Resonance Spectroscopy↗

PubMedDate not supplied

Gadolinium-DTPA enhancement of experimental soft tissue carcinoma and hemorrhage in magnetic resonance imaging.

An experimental series in the rabbit was performed to test gadolinium-DTPA (Gd-DTPA) enhancement of VX-2 carcinoma and hemorrhages induced in the soft tissues. The recognition of both malignant and benign lesions was greatly facilitated on T1 weighted images after intravenous administration of 0.3 mmol Gd-DTPA/kg body weight because of reduced T1 relaxation times. Gd-DTPA enhancement reached its maximum after 10-15 minutes and was most apparent in tumor tissue, connective tissue surrounding the tumor and in the area of fresh hemorrhage.

Animals↗

PubMedDate not supplied

Gadolinium-DTPA enhancement of VX-2 carcinoma of the rabbit kidney on T1 weighted magnetic resonance images.

Experimental renal carcinoma was induced by percutaneous injection of VX-2 carcinoma cells into the left kidney in New Zealand white rabbits. Magnetic resonance imaging (MRI) was performed at 0.15 T before and after intravenous injection of 0.3 mmol gadolinium-DTPA (Gd-DTPA) per kg body weight. Gd-DTPA enhanced the tumors by increasing the signal intensity on T1 weighted images. The enhancement was evident immediately after Gd-DTPA injection, increasing during the observation time of 30 minutes. Histologically the areas of enhancement corresponded well to the viable tumor tissue.

Animals↗