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Biomedical subjects

R E Herron

Publications and source records attributed to R E Herron.

12 recordsLinked to original sources

An innovative approach to reducing medical care utilization and expenditures.

In a retrospective study, we assessed the impact on medical utilization and expenditures of a multicomponent prevention program, the Maharishi Vedic Approach to Health (MVAH). We compared archival data from Blue Cross/Blue Shield Iowa for MVAH (n = 693) with statewide norms for 1985 through 1995 (n = 600,000) and with a demographically matched control group (n = 4,148) for 1990, 1991, 1994, and 1995. We found that the 4-year total medical expenditures per person in the MVAH group were 59% and 57% lower than those in the norm and control groups, respectively; the 11-year mean was 63% lower than the norm. The MVAH group had lower utilization and expenditures across all age groups and for all disease categories. Hospital admission rates in the control group were 11.4 times higher than those in the MVAH group for cardiovascular disease, 3.3 times higher for cancer, and 6.7 times higher for mental health and substance abuse. The greatest savings were seen among MVAH patients older than age 45, who had 88% fewer total patients days compared with control patients. Our results confirm previous research supporting the effectiveness of MVAH for preventing disease. Our evaluation suggests that MVAH can be safely used as a cost-effective treatment regimen in the managed care setting.

Adult↗

The pharmacological effects of the ligroin extract of nutmeg (Myristica fragrans).

A ligroin extract of nutmeg (Myristica fragrans) caused a significant increase in the duration of light and deep sleep in the young chicken. The presence of trimyristin tended to increase the effect of the extract. The extract did not contain detectable amounts of myristicin, elemicin, safrole, or eugenol, which either individually or collectively have been suggested to be the active agent of nutmeg.

Animals↗

Breast cancer detection utilizing biostereometric analysis.

Twelve female patients participated in a study designed to employ computer-assisted biostereometric analysis for the detection of breast masses. All breast masses were previously documented by physical examination and followed by xeromammography, stereophotography, and histopathologic confirmation of tumor type. "Contour mammograms" were produced from the biostereometric photographs. These data were analyzed first for tumor detection and location by visual inspection. A second analysis employed a computed algorithm designed to locate and measure surface aberrations that suggest the possibility of underlying breast tumor. Visual analysis yielded the exact location of breast tumors in eight of the ten malignancies; computer analysis exactly located nine of the ten malignancies. In the computer analysis, one malignancy not exactly located by quadrant was, nevertheless, located in the correct breast. The results of the study suggest that the biostereometric process may have future use in screening or prescreening procedures for breast cancer detection. It is noninvasive, applicable to large numbers of women and with suitable refinements, and capable of being fully automated.

Aged↗

Evoked EEG responses in several motor areas of brain to stimulation of hippocampus and caudate, alone and in combination.

In curarized rats, electrical stimulation (6 Hz pulses in 6-sec trains) was delivered either to the dorsal hippocampus (Hip), the caudate nucleus (Caud), or to both. Hip and Caud stimulation evoked activity in the motor cortex and the Hip, and the responses commonly grew larger during the stimulation; to a lesser extent, responses occurred in the brainstem reticulum and cerebellar cortex. Combined Hip and Caud stimulation responses were often greater than the responses to stimulation of either Hip or Caud alone, but less than the sum of responses from each single-site stimulation, suggesting occlusive interference because of shared elements in the projection pathways. There were also some instances suggesting mutual facilitation, where the responses to combined stimulation were greater than the sum of the responses to each single-site stimulation. Both kinds of results seem to indicate that the hippocampus, as well as the caudate, has functional connections with motor control areas of the brain and that both areas may interact in motor control.

Animals↗

Biostereometric analysis of body form: the second manned Skylab mission.

Biostereometrics is the measurement and the mathematical description of the three-dimensional form of biological objects. Stereophotogrammetry was used to derive the Cartesian coordinates of numerous points on the body surface of the Skylab crewmen, both before and after flight, on all three Skylab missions. Mathematical analysis of the coordinate description allows the computation of surface area and volume of the body, as well as the volume of body segments, and the area and shape of cross sections. Loss of body weight in the first two Skylab flight crews was accompanied by comparable loss of volume and little change in density. Volume loss wad divided about equally between the trunk and the legs; however, because the volume of the legs is less than that of the trunk, this finding represented a greater proportional volume loss in the legs. Comparison of cross-sectional areas suggests that the calf undergoes shrinkage to a greater extent than does the thigh. The suggested interpretation of these changes is that, during flight, a reduction in bulk of many of the body tissues occurs. This reduction is probably caused, at least in part, by disuse atrophy of skeletal muscles in the absence of gravity. The atrophy is lessened to some extent by the in-flight exercise program. The stereoscopic images of the crewmen from a permanent archival record of body form on which more detailed measurements may be made in the future.

Adult↗

Biostereometrics and the communication of biological form.

Biostereometrics-the spatial and spatio-temporal analysis of biological form and function based on principles geometry-is a modern approach to the measurement and analysis of biological form which recognizes that organic structures are irregular and three-dimensional (or four-dimensional, as in movement or growth). Stereometric sensors of various types are used to determine the coordinates of points distributed over the surface (internal or external). The resulting data provide a more comprehensive, parsimonious and unambiguous spatial quantification than heretofore possible using traditional lengths, breadths, and circumferences. Recent and prospective biomedical applications are described.

Anthropometry↗

The impact of the transcendental meditation program on government payments to physicians in Quebec.

PURPOSE: This study evaluated whether governmental medical payments in Quebec were affected by the Transcendental Meditation (TM) technique. DESIGN: This retrospective study used a pre- and postintervention design in which government payments for physicians' services were reviewed for 3 years before and up to 7 years after subjects started the technique. Payment data were adjusted for aging and year-specific variation (including inflation) using normative data. No separate control group was used; thus it is impossible to determine whether the changes were caused by the TM program or some other factor. SUBJECTS: A volunteer group of 677 provincial health insurance enrollees was evaluated. The subjects had chosen to practice the TM technique before they were selected to enter the study. The subjects (348 men, 329 women) had diverse occupations. Their average age was 38 years and ranged from 18 to 71 years at the start of the TM program. INTERVENTION: The TM technique of Maharishi Mahesh Yogi is a standardized procedure practiced for 15 to 20 minutes twice daily while sitting comfortably with eyes closed. SETTING: Province of Quebec, Canada. RESULTS: During the 3 years before starting the TM program, the adjusted payments to physicians for treating the subjects did not change significantly. After beginning TM practice, subjects' adjusted expenses declined significantly. The several methods used to assess the rate of decline showed estimates ranging from 5% to 7% annually. CONCLUSIONS: The results suggests that the TM technique reduces government payments to physicians. However, because of the sampling method used, the generalizability of these results to wider populations could not be evaluated.

Adolescent↗

The impact of the transcendental meditation program on government payments to physicians in Quebec: an update.

PURPOSE: To determine whether practice of the Transcendental Meditation (TM) technique can affect medical expenses. DESIGN: The evaluation was a quasi experimental, longitudinal, cost-minimization study. SETTING: Province of Quebec, Canada. SUBJECTS: This study involved 1418 Quebec health insurance enrollees who practiced the TM technique compared with 1418 subjects who were randomly selected from enrollees of the same age, sex, and region. TM subjects had chosen to begin the technique prior to learning about and choosing to enter the study. MEASURES: This 14-year, pre- and postintervention study retrospectively assessed government payments to physicians for treating the TM and comparison groups. Other medical expense data for individuals were unavailable. Data were inflation-adjusted. For each subject, least squares regression slopes were calculated to estimate pre- and postintervention annual rates of change in payments. We compared the groups' means and 1%, 5%, and 10% trimmed means (robust estimators) of the slopes. RESULTS: Before starting meditation, the yearly rate of increase in payments between groups was not significantly different (p > .17). After commencing meditation, the TM group's mean payments declined 1% to 2% annually. The comparison group's payments increased up to 11.73% annually over 6 years. There was a 13.78% mean annual difference (p = .0017). CONCLUSIONS: The results suggest that the TM technique reduced payments to physicians between 5% and 13% annually relative to comparison subjects over 6 years. Randomized studies are recommended.

Adult↗