Biomedical subjects
Publications and source records attributed to R E Kalb.
A 60-year-old man with allergic contact dermatitis to clotrimazole (Lotrimin) is described. Results of patch tests confirmed the reaction to clotrimazole itself and not the vehicle. After negative results of patch tests to other imidazoles, the patient was treated with econazole without complications. A brief review of contact dermatitis to clotrimazole and other imidazoles is included.
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A significant linear correlation was found between serum total porphyrin concentration and 24-hour total urinary porphyrin excretion in 18 patients with porphyria cutanea tarda sampled at diagnosis and during and after treatment on 73 occasions. This confirms that the serum porphyrin level parallels urinary porphyrin excretion and is an appropriate indicator of disease activity useful for monitoring patients in clinical practice.